Introduction:Basic information about CAS 479035-75-1|meta-Fexofenadine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | meta-Fexofenadine |
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| CAS Number | 479035-75-1 | Molecular Weight | 501.65600 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C32H39NO4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | meta-Fexofenadine |
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| Synonym | More Synonyms |
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meta-Fexofenadine BiologicalActivity
| Description | meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine[1]. Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial[2]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Maher HM, et al. Development of validated stability-indicating chromatographic method for the determination of fexofenadine hydrochloride and its related impurities in pharmaceutical tablets. Chem Cent J. 2011 Dec 3;5(1):76. [2]. Watanabe N, et al. The effects of fexofenadine on eosinophilia and systemic anaphylaxis in mice infected with Trichinella spiralis. Int Immunopharmacol. 2004 Mar;4(3):367-75. |
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Chemical & Physical Properties
| Molecular Formula | C32H39NO4 |
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| Molecular Weight | 501.65600 |
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| Exact Mass | 501.28800 |
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| PSA | 81.00000 |
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| LogP | 5.44840 |
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| InChIKey | RYHUKJMCYGRCSM-UHFFFAOYSA-N |
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| SMILES | CC(C)(C(=O)O)c1cccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)c1 |
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Synonyms
| Fexofenadine impurity B |
| 2-[3-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid |