CAS 479035-75-1|meta-Fexofenadine

Introduction:Basic information about CAS 479035-75-1|meta-Fexofenadine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namemeta-Fexofenadine
CAS Number479035-75-1Molecular Weight501.65600
Density/Boiling Point/
Molecular FormulaC32H39NO4Melting Point/
MSDS/Flash Point/

Names

Namemeta-Fexofenadine
SynonymMore Synonyms

meta-Fexofenadine BiologicalActivity

Descriptionmeta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine[1]. Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial[2].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References

[1]. Maher HM, et al. Development of validated stability-indicating chromatographic method for the determination of fexofenadine hydrochloride and its related impurities in pharmaceutical tablets. Chem Cent J. 2011 Dec 3;5(1):76.

[2]. Watanabe N, et al. The effects of fexofenadine on eosinophilia and systemic anaphylaxis in mice infected with Trichinella spiralis. Int Immunopharmacol. 2004 Mar;4(3):367-75.

Chemical & Physical Properties

Molecular FormulaC32H39NO4
Molecular Weight501.65600
Exact Mass501.28800
PSA81.00000
LogP5.44840
InChIKeyRYHUKJMCYGRCSM-UHFFFAOYSA-N
SMILESCC(C)(C(=O)O)c1cccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)c1

Synonyms

Fexofenadine impurity B
2-[3-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid
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