CAS 637-03-6|Arsine, oxophenyl-

Introduction:Basic information about CAS 637-03-6|Arsine, oxophenyl-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameArsine, oxophenyl-
CAS Number637-03-6Molecular Weight168.025
Density1Boiling Point100ºC
Molecular FormulaC6H5AsOMelting Point145-148 °C
MSDSChineseUSAFlash Point/
Symbol
GHS06, GHS09
Signal WordDanger

Names

Namephenylarsine oxide
SynonymMore Synonyms

Chemical & Physical Properties

Density1
Boiling Point100ºC
Melting Point145-148 °C
Molecular FormulaC6H5AsO
Molecular Weight168.025
Exact Mass167.955643
PSA17.07000
LogP0.47410
Appearance of Characterspowder | white to yellow
InChIKeyBQVCCPGCDUSGOE-UHFFFAOYSA-N
SMILESO=[As]c1ccccc1
Storage conditionPoison room
StabilityStable.
Water SolubilityDMSO: 50 mg/mL

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CH8100000
CHEMICAL NAME :
Arsine, oxophenyl-
CAS REGISTRY NUMBER :
637-03-6
BEILSTEIN REFERENCE NO. :
2935227
LAST UPDATED :
199710
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C6-H5-As-O
MOLECULAR WEIGHT :
168.03
WISWESSER LINE NOTATION :
O-AS-R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1930 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,210,1942
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1570 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHBUA9 Pharmaceutical Bulletin. (Tokyo, Japan) V.1-5, 1953-57. For publisher information, see CPBTAL. Volume(issue)/page/year: 2,19,1954
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1900 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 70,221,1940
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
790 ug/kg
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 69,342,1940 *** U.S. STANDARDS AND REGULATIONS *** OSHA PEL (Gen Indu):8H TWA 0.5 mg(As)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.5 mg(As)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.5 mg(As)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.5 mg(As)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1555 No. of Facilities: 191 (estimated) No. of Industries: 10 No. of Occupations: 16 No. of Employees: 5958 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1555 No. of Facilities: 606 (estimated) No. of Industries: 7 No. of Occupations: 6 No. of Employees: 1922 (estimated) No. of Female Employees: 695 (estimated)

Safety Information

Symbol
GHS06, GHS09
Signal WordDanger
Hazard StatementsH301 + H331-H410
Precautionary StatementsP261-P273-P301 + P310-P311-P501
Hazard CodesT:Toxic;N:Dangerousfortheenvironment;
Risk PhrasesR23/25;R50/53
Safety PhrasesS20/21-S28-S45-S60-S61
RIDADRUN 3465 6.1/PG 3
WGK Germany3
RTECSCH8100000
Packaging GroupIII
Hazard Class6.1

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Synonyms

Arsine, oxophenyl-
EINECS 211-275-3
Oxo(phenyl)arsine
Phenylarsine oxide
oxo(phenyl)arsane
arsorosobenzene
Phenyl arsenoxide
MFCD00001990
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