Introduction：Basic information about CAS 4548-34-9|Tranylcypromine (2-PCPA) HCl, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tranylcypromine (2-PCPA) HCl |
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| CAS Number | 4548-34-9 | Molecular Weight | 169.65100 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C9H12ClN | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | tranylcypromine hydrochloride |
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| Synonym | More Synonyms |
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Tranylcypromine (2-PCPA) HCl BiologicalActivity
| Description | (1S,2R)-Tranylcypromine hydrochloride is a potent antidepressant agent. (1S,2R)-Tranylcypromine hydrochloride can inhibits MAO and LSD1[1][2]. |
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| Related Catalog | Signaling Pathways >>Epigenetics >>Histone DemethylaseSignaling Pathways >>Neuronal Signaling >>Monoamine OxidaseResearch Areas >>Neurological Disease |
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| References | [1]. TetsuyaEzawa, et al. Amidation of carboxylic acids via the mixed carbonic carboxylic anhydrides and its application to synthesis of antidepressant (1S,2R)-tranylcypromine. Tetrahedron: Asymmetry. 15 December 2017;28(12):1690-1699. [2]. Valente S, et al. Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell Studies. ACS Med Chem Lett. 2014 Dec 8;6(2):173-7. |
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Chemical & Physical Properties
| Molecular Formula | C9H12ClN |
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| Molecular Weight | 169.65100 |
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| Exact Mass | 169.06600 |
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| PSA | 26.02000 |
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| LogP | 3.00350 |
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| InChIKey | ZPEFMSTTZXJOTM-MTFPJWTKSA-N |
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| SMILES | Cl.NC1CC1c1ccccc1 |
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| Storage condition | -20℃ |
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Synonyms
| Tranylcypromine (2-PCPA) HCl |
| (1S,2R)-2-Phenylcyclopropan-1-amine hydrochloride |
| Tranylcypromine |
| (+)-TRANYLCYPROMINE HYDROCHLORIDE |
