CAS 3387-36-8|5'-UMP disodium salt

Introduction：Basic information about CAS 3387-36-8|5'-UMP disodium salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 5'-UMP disodium salt BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Synonyms

Common Name	5'-UMP disodium salt
CAS Number	3387-36-8	Molecular Weight	368.14
Density	1.865g/cm3	Boiling Point	/
Molecular Formula	C₉H₁₁N₂Na₂O₉P	Melting Point	208-210 °C
MSDS	USA	Flash Point	/

Names

Name	Disodium uridine-5'-monophosphate
Synonym	More Synonyms

5'-UMP disodium salt BiologicalActivity

Description	Uridine 5'-monophosphate disodium salt is component used for RNA synthesis.
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. Hozumi Y, et al. Orotate phosphoribosyltransferase localizes to the Golgi complex and its expression levels affect the sensitivity to anti-cancer drug 5-fluorouracil. Biomed Res. 2015;36(6):403-9.

Chemical & Physical Properties

Density	1.865g/cm3
Melting Point	208-210 °C
Molecular Formula	C₉H₁₁N₂Na₂O₉P
Molecular Weight	368.14
Exact Mass	367.999756
PSA	186.78000
Index of Refraction	-14 ° (C=1, H2O)
InChIKey	KURVIXMFFSNONZ-WFIJOQBCSA-L
SMILES	O=c1ccn(C2OC(COP(=O)([O-])[O-])C(O)C2O)c(=O)[nH]1.[Na+].[Na+]
Storage condition	−20°C
Water Solubility	40 g/100 mL (20 ºC)

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YU7975000

CHEMICAL NAME :: Uridine, 5'-dihydrogen phosphate, disodium salt

CAS REGISTRY NUMBER :: 3387-36-8

LAST UPDATED :: 199712

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C9-H11-N2-O9-P.2Na

MOLECULAR WEIGHT :: 368.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >12 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 22,618,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3111 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 22,618,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >6 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Skin and Appendages - dermatitis, irritative (after systemic exposure)

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 22,618,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >12 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 22,618,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3394 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 22,618,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3698 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 22,618,1975

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	YU7975000

Synonyms

Disodium Uridine-5-Monophosphate

5'-UMP disodium salt

EINECS 222-211-9

Disodium uridine 5'-phosphate

5'-UMP-NA2

5`-UMP,2Na

5'-UMP 2Na Hydrate

Uridine 5'-Monophosphate Disodium Salt Hydrate

disodiumump

disodium salt of uridine 5'-monophosphate

Disodium 5'-O-phosphonatouridine

MFCD00006525

5'-Uridylic Acid Disodium Salt Hydrate

uridine 5'-monophosphate disodium salt

5′-UMP-Na2

5'-Uridylic acid, sodium salt (1:2)

uridine-5'-monophosphoric acid disodium salt

Uridylic acid disodium salt

uridine-5′-monophosphate disodium

UMP 2NA

5'-Uridylic acid disodium salt

Uridine 5‘-monophosphate,disodium salt,hydrate

Uridine-5'--monophosphate,Disodium salt

UMP,NA2

D-uridine-5'-monophosphate disodium salt

Disodium uridine 5'-monophosphate

UMP DISODIUM

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