Introduction：Basic information about CAS 456-88-2|3-Fluoro-DL-phenylalanine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
H-DL-Phe(3-F)-OH is a phenylalanine derivative[1].
Related Catalog
Research Areas >>OthersSignaling Pathways >>Others >>Others
In Vitro
Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References
[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-819.
Chemical & Physical Properties
Density
1.3±0.1 g/cm3
Boiling Point
305.0±32.0 °C at 760 mmHg
Melting Point
-240ºC(dec.)
Molecular Formula
C9H10FNO2
Molecular Weight
183.180
Flash Point
138.3±25.1 °C
Exact Mass
183.069550
PSA
63.32000
LogP
1.16
Vapour Pressure
0.0±0.7 mmHg at 25°C
Index of Refraction
1.555
InChIKey
VWHRYODZTDMVSS-UHFFFAOYSA-N
SMILES
NC(Cc1cccc(F)c1)C(=O)O
Toxicological Information
CHEMICAL IDENTIFICATION
RTECS NUMBER :
AY6300000
CHEMICAL NAME :
Alanine, 3-(m-fluorophenyl)-
CAS REGISTRY NUMBER :
456-88-2
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H10-F-N-O2
MOLECULAR WEIGHT :
183.20
WISWESSER LINE NOTATION :
QVYZ1R CF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 73,176,1941
Safety Information
Personal Protective Equipment
dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes
Xi: Irritant;
Risk Phrases
R37
Safety Phrases
24/25
RIDADR
NONH for all modes of transport
WGK Germany
3
HS Code
2922499990
Customs
HS Code
2922499990
Summary
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%
Articles28
More Articles
Hidden overflow pathway to L-phenylalanine in Pseudomonas aeruginosa.
J. Bacteriol. 154(2) , 623-31, (1983)
Pseudomonas aeruginosa is representative of a large group of pseudomonad bacteria that possess coexisting alternative pathways to L-phenylalanine (as well as to L-tyrosine). These multiple flow routes...
19F n.m.r. studies of conformational changes accompanying cyclic AMP binding to 3-fluorophenylalanine-containing cyclic AMP receptor protein from Escherichia coli.
Biochem. J. 287 ( Pt 2) , 627-32, (1992)
A fluorine-containing analogue of the cyclic AMP (cAMP) receptor protein (CRP) from Escherichia coli was prepared by biosynthetic incorporation of 3-fluorophenylalanine (3-F-Phe). 19F n.m.r. studies o...
Fluorine-19 nuclear magnetic resonance spectroscopic study of fluorophenylalanine- and fluorotryptophan-labeled avian egg white lysozymes.
Biochemistry 33(17) , 5238-45, (1994)
We report the 470-MHz (11.7 T) 19F solution nuclear magnetic resonance (NMR) spectra of 2-, 3-, and 4-fluorophenylalanine incorporated into the egg white lysozymes (EC 3.2.1.17) of chicken, pheasant, ...
