Introduction：Basic information about CAS 195867-54-0|Histamine trifluromethyl toluidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Histamine trifluromethyl toluidine |
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| CAS Number | 195867-54-0 | Molecular Weight | 614.56800 |
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| Density | / | Boiling Point | 922.2ºC at 760mmHg |
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| Molecular Formula | C27H33F3N4O9 | Melting Point | / |
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| MSDS | / | Flash Point | 511.5ºC |
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Names
| Name | HTMT dimaleate,6-[2-(4-Imidazolyl)ethylamino]-N-(4-trifluoromethylphenyl)heptanecarboxamidedimaleate |
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| Synonym | More Synonyms |
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Histamine trifluromethyl toluidine BiologicalActivity
| Description | HTMT (dimaleate) is a potent histamine H1 and H2 receptor agonist. HTMT (dimaleate) is 4 x 104 times more active than histamine in H2-mediated effects in natural suppressor cells[1]. |
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| Related Catalog | Signaling Pathways >>Immunology/Inflammation >>Histamine ReceptorResearch Areas >>Inflammation/ImmunologySignaling Pathways >>GPCR/G Protein >>Histamine Receptor |
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| Target | H1 Receptor H2 Receptor |
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| References | [1]. Khan MM, Marr-Leisy D, Verlander MS, Bristow MR, Strober S, Goodman M, Melmon KL. The effects of derivatives of histamine on natural suppressor cells. J Immunol. 1986 Jul 1;137(1):308-14. |
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Chemical & Physical Properties
| Boiling Point | 922.2ºC at 760mmHg |
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| Molecular Formula | C27H33F3N4O9 |
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| Molecular Weight | 614.56800 |
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| Flash Point | 511.5ºC |
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| Exact Mass | 614.22000 |
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| PSA | 219.01000 |
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| LogP | 4.03570 |
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| Vapour Pressure | 0mmHg at 25°C |
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| InChIKey | YRZCXESTJQMPMD-BTJKTKAUSA-N |
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| SMILES | CC(CCCCC(=O)Nc1ccc(C(F)(F)F)cc1)NCCc1cnc[nH]1.O=C(O)C=CC(=O)O |
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| Storage condition | 2-8°C |
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Safety Information
Synonyms
