CAS 5255-17-4|3b-Hydroxy-5-cholenoic acid
| Common Name | 3b-Hydroxy-5-cholenoic acid | ||
|---|---|---|---|
| CAS Number | 5255-17-4 | Molecular Weight | 374.55700 |
| Density | 1.11 g/cm3 | Boiling Point | 522.8ºC at 760 mmHg |
| Molecular Formula | C24H38O3 | Melting Point | 232ºC |
| MSDS | USA | Flash Point | 284.1ºC |
Names
| Name | 3beta-hydroxy-delta5-cholenic acid |
|---|---|
| Synonym | More Synonyms |
3b-Hydroxy-5-cholenoic acid BiologicalActivity
| Description | 3b-Hydroxy-5-cholenoic acid is a monohydroxy bile acid of endogenous origin and could be found in children with the syndrome of hepatic ductular hypoplasia. |
|---|---|
| Related Catalog | Natural Products >>Acids and AldehydesResearch Areas >>Metabolic Disease |
| Target | Human Endogenous Metabolite |
| References | [1]. Back P, et al. Identification of 3 beta-hydroxy-5-cholenoic acid in human meconium. Hoppe Seylers Z Physiol Chem. 1973 Jan;354(1):83-9. |
Chemical & Physical Properties
| Density | 1.11 g/cm3 |
|---|---|
| Boiling Point | 522.8ºC at 760 mmHg |
| Melting Point | 232ºC |
| Molecular Formula | C24H38O3 |
| Molecular Weight | 374.55700 |
| Flash Point | 284.1ºC |
| Exact Mass | 374.28200 |
| PSA | 57.53000 |
| LogP | 5.42720 |
| Index of Refraction | -39.5 ° (C=1, Dioxane) |
| InChIKey | HIAJCGFYHIANNA-QIZZZRFXSA-N |
| SMILES | CC(CCC(=O)O)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles20
More Articles| Hepatic bile salt sulfotransferases in the rat: sulfation of 3 beta-hydroxy-5-cholenoate during development. J. Pediatr. Gastroenterol. Nutr. 12(2) , 260-8, (1991) Bile salt sulfotransferase (BSS) activity for the fetal bile acid, 3 beta-hydroxy-5-cholenoate, was first detected in the fetus at 18-19 days of gestation and was twofold greater than for glycolithoch... | |
| Determination of 3 beta-hydroxy-5-cholen-24-oic acid and its sulfate in human serum by gas chromatography-mass spectrometry. Steroids 44(1) , 47-55, (1984) The glycine conjugate of 3 beta-hydroxy-5-cholen-24-oic acid and its sulfate labeled with deuterium at the C-2, -4, and -23 positions were synthesized. A highly sensitive and specific quantitative ass... | |
| Unusual serum bile acid pattern in children with the syndrome of hepatic ductular hypoplasia. Clin. Chim. Acta 145(3) , 289-96, (1985) Fasting bile acids in serum of eight children with the syndrome of hepatic ductular hypoplasia were analyzed by gas chromatography. The children did not receive any kind of treatment during the month ... |
Synonyms
| MFCD00069468 |
| Cholenic acid |
| 3b-Hydroxy-5-cholenoic acid |
| 5-cholenic acid-3B-ol |
| 5-CHOLENIC ACID-3BETA-OL |
| 3β-Hydroxy-DELTA5-cholenic Acid |
