CAS 472-26-4|Telocinobufagin

Introduction：Basic information about CAS 472-26-4|Telocinobufagin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Telocinobufagin BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Synonyms

Common Name	Telocinobufagin
CAS Number	472-26-4	Molecular Weight	402.524
Density	1.3±0.1 g/cm3	Boiling Point	589.6±50.0 °C at 760 mmHg
Molecular Formula	C₂₄H₃₄O₅	Melting Point	/
MSDS	/	Flash Point	201.0±23.6 °C

Names

Name	5-[(3S,5S,8R,9S,10R,13R,14S,17R)-3,5,14-trihydroxy-10,13-dimethyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pyran-2-one
Synonym	More Synonyms

Telocinobufagin BiologicalActivity

Description	Telocinobufagin is one of anti-hepatoma constituent in Venenum Bufonis.
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>OthersNatural Products >>Steroids

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	589.6±50.0 °C at 760 mmHg
Molecular Formula	C₂₄H₃₄O₅
Molecular Weight	402.524
Flash Point	201.0±23.6 °C
Exact Mass	402.240631
PSA	90.90000
LogP	1.78
Vapour Pressure	0.0±3.8 mmHg at 25°C
Index of Refraction	1.624
InChIKey	PBSOJKPTQWWJJD-ZBDZJSKLSA-N
SMILES	CC12CCC(O)CC1(O)CCC1C2CCC2(C)C(c3ccc(=O)oc3)CCC12O
Storage condition	-20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EI2996700

CHEMICAL NAME :: 5-beta-Bufa-20,22-dienolide, 3-beta,5,14-trihydroxy-

CAS REGISTRY NUMBER :: 472-26-4

BEILSTEIN REFERENCE NO. :: 0056287

LAST UPDATED :: 199709

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C24-H34-O5

MOLECULAR WEIGHT :: 402.58

WISWESSER LINE NOTATION :: L E5 B666TJ A1 E1 IQ MQ OQ F- ET6OVJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4340 ug/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - antipsychotic

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 24,1714,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 102 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHUZBI Pharmazie in Unserer Zeit. (VCH Pub., Inc., 303 N.W. 12th Ave., Deerfield Beach, FL 33441) V.1- 1972- Volume(issue)/page/year: 13,129,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 100 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85ELDJ "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963 Volume(issue)/page/year: -,194,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 1102 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHUZBI Pharmazie in Unserer Zeit. (VCH Pub., Inc., 303 N.W. 12th Ave., Deerfield Beach, FL 33441) V.1- 1972- Volume(issue)/page/year: 13,129,1984

Synonyms

3,5,14-Trihydroxybufa-20,22-dienolide

Telobufotoxin

5β-Bufa-20,22-dienolide, 3β,5,14-trihydroxy-

Telecinobufagin

Telocinobufogenin

(3β,5β)-3,5,14-Trihydroxybufa-20,22-dienolide

Bufa-20,22-dienolide, 3,5,14-trihydroxy-, (3β,5β)-

Telocinobufagin

Recommended......