Introduction：Basic information about CAS 27856-54-8|Lamiide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Lamiide |
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| CAS Number | 27856-54-8 | Molecular Weight | 422.381 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 667.2±55.0 °C at 760 mmHg |
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| Molecular Formula | C17H26O12 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 237.8±25.0 °C |
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Names
| Name | lamiide |
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| Synonym | More Synonyms |
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Lamiide BiologicalActivity
| Description | Lamiide, an orally active iridoid compound, can be found in Bouchea fluminensis leaves. Lamiide exhibits anti-inflammatory and anti-lipoperoxidative activity[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| In Vitro | Lamiide inhibits rat-brain phospholipid peroxidation, with an IC50 of 0.92 mM[1]. |
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| In Vivo | Lamiide (12.5-100 mg/kg; p.o. 30 min before Carrageenin injection) dose-dependently reduces Carrageenin-induced edema[1]. Animal Model: Female Wistar rats (8-weeks old, 150-200 g) were injected with Carrageenin in the subplantar aponeurosis of the right hind paw[1] Dosage: 12.5, 25, 50, 100 mg/kg Administration: P.o. 30 min before Carrageenin injection Result: Reduced Carrageenin-induced edema, with an ED50 of 62.3 mg/kg. |
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| References | [1]. Delaporte RH, et, al. Anti-inflammatory activity and lipid peroxidation inhibition of iridoid lamiide isolated from Bouchea fluminensis (Vell.) Mold. (Verbenaceae). J Ethnopharmacol. 2002 Oct;82(2-3):127-30. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 667.2±55.0 °C at 760 mmHg |
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| Molecular Formula | C17H26O12 |
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| Molecular Weight | 422.381 |
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| Flash Point | 237.8±25.0 °C |
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| Exact Mass | 422.142426 |
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| PSA | 195.60000 |
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| LogP | -3.03 |
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| Vapour Pressure | 0.0±4.6 mmHg at 25°C |
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| Index of Refraction | 1.644 |
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| InChIKey | VFYACENSDOLJGQ-SNONCDODSA-N |
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| SMILES | COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C2C1(O)CC(O)C2(C)O |
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| Storage condition | ?20°C |
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Safety Information
| RIDADR | NONH for all modes of transport |
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Synonyms
| Methyl (1S,4aR,6S,7R,7aS)-1-(β-D-glucopyranosyloxy)-4a,6,7-trihydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate |
| Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-4a,6,7-trihydroxy-7-methyl-, methyl ester, (1S,4aR,6S,7R,7aS)- |
