CAS 98426-48-3|N-Butanoyl-DL-homoserine lactone

Introduction:Basic information about CAS 98426-48-3|N-Butanoyl-DL-homoserine lactone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameN-Butanoyl-DL-homoserine lactone
CAS Number98426-48-3Molecular Weight171.19400
Density/Boiling Point/
Molecular FormulaC8H13NO3Melting Point/
MSDSChineseUSAFlash Point/

Names

NameN-butyryl-DL-homoserine lactone
SynonymMore Synonyms

N-Butanoyl-DL-homoserine lactone BiologicalActivity

DescriptionN-Butanoyl-DL-homoserine lactone ((Rac)-C4-HSL) is a quorum sensing (QS) signaling molecule. N-Butanoyl-DL-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[1].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Others >>Others
In VitroThe dissociation constant (Kd value) of aptamer binding to N-Butanoyl-DL-homoserine lactone is 28.47 nM[1].
References

[1]. Zhao M, et al. C4-HSL aptamers for blocking qurom sensing and inhibiting biofilm formation in Pseudomonas aeruginosa and its structure prediction and analysis. PLoS One. 2019 Feb 19;14(2):e0212041.

Chemical & Physical Properties

Molecular FormulaC8H13NO3
Molecular Weight171.19400
Exact Mass171.09000
PSA55.40000
LogP0.60910
InChIKeyVFFNZZXXTGXBOG-UHFFFAOYSA-N
SMILESCCCC(=O)NC1CCOC1=O
Storage condition2-8℃

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases22-24/25
RIDADRNONH for all modes of transport
HS Code2932209090

Customs

HS Code2932209090
Summary2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles7

More Articles
Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones.

Microbiology 143 , 3703, (1997)

Quorum sensing relies upon the interaction of a diffusible signal molecule with a transcriptional activator protein to couple gene expression with cell population density. In Gram-negative bacteria, s...

Detection of acyl-homoserine lactones by Escherichia and Salmonella.

Curr. Opin. Microbiol. 14 , 188-193, (2011)

Escherichia and Salmonella do not synthesize quorum-sensing signaling molecules of the N-acyl-l-homoserine lactone (AHL) type but they can detect AHLs produced by other species of bacteria. AHLs are p...

N-acyl homoserinelactone-mediated gene regulation in gram-negative bacteria.

Syst. Appl. Microbiol. 22 , 493-506, (1999)

The view of bacteria as unicellular organisms has strong roots in the tradition of culturing bacteria in liquid media. However, in nature microbial activity is mainly associated with surfaces where ba...

Synonyms

MFCD018629
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