Introduction：Basic information about CAS 63-12-7|benzquinamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | benzquinamide |
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| CAS Number | 63-12-7 | Molecular Weight | 404.50000 |
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| Density | 1.2±0.1g/cm3 | Boiling Point | 531.0±50.0°C at 760 mmHg |
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| Molecular Formula | C22H32N2O5 | Melting Point | / |
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| MSDS | / | Flash Point | 274.9±30.1°C |
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Names
| Name | benzquinamide |
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| Synonym | More Synonyms |
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benzquinamide BiologicalActivity
| Description | Benzquinamide is an antiemetic which can bind to the α2A, α2B, and α2C adrenergic receptors (α2-AR) with Ki values of 1,365, 691, and 545 nM, respectively. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Metabolic Disease |
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| Target | Ki: 1,365 nM (α2A), 691 nM (α2B), 545 nM (α2C)[1]. |
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| References | [1]. Elisabet Gregori-Puigjané, et al. Identifying mechanism-of-action targets for drugs and probes. Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28): 11178-11183. doi: 10.1073/pnas.1204524109 |
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Chemical & Physical Properties
| Density | 1.2±0.1g/cm3 |
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| Boiling Point | 531.0±50.0°C at 760 mmHg |
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| Molecular Formula | C22H32N2O5 |
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| Molecular Weight | 404.50000 |
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| Flash Point | 274.9±30.1°C |
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| Exact Mass | 404.23100 |
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| PSA | 68.31000 |
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| LogP | 2.36090 |
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| InChIKey | JSZILQVIPPROJI-UHFFFAOYSA-N |
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| SMILES | CCN(CC)C(=O)C1CN2CCc3cc(OC)c(OC)cc3C2CC1OC(C)=O |
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Synonyms
