CAS 344298-93-7|l-lysine-3,3,4,4,5,5,6,6-d8 hcl
| Common Name | l-lysine-3,3,4,4,5,5,6,6-d8 hcl | ||
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| CAS Number | 344298-93-7 | Molecular Weight | 190.69800 |
| Density | / | Boiling Point | / |
| Molecular Formula | C6H7ClD8N2O2 | Melting Point | 263-264ºC (dec.)(lit.) |
| MSDS | USA | Flash Point | / |
Names
| Name | l-lysine-3,3,4,4,5,5,6,6-d8 hcl |
|---|---|
| Synonym | More Synonyms |
l-lysine-3,3,4,4,5,5,6,6-d8 hcl BiologicalActivity
| Description | L-Lysine-d8 hydrochloride is the deuterium labeled L-Lysine hydrochloride. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseResearch Areas >>EndocrinologyResearch Areas >>InfectionResearch Areas >>Inflammation/Immunology |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Al-Malki AL, et al. Suppression of acute pancreatitis by L-lysinein mice. BMC Complement Altern Med. 2015 Jun 23;15:193. [3]. Shimomura A, et al. Dietary L-lysineprevents arterial calcification in adenine-induced uremic rats. J Am Soc Nephrol. 2014 Sep;25(9):1954-65. [4]. Al-Malki AL, et al. Suppression of acute pancreatitis by L-lysinein mice. BMC Complement Altern Med. 2015 Jun 23;15:193. [5]. Al-Malki AL, et al. Suppression of acute pancreatitis by L-lysinein mice. BMC Complement Altern Med. 2015 Jun 23;15:193. [6]. Baruffol C, et al. L-lysine dose dependently delays gastric emptying and increases intestinal fluid volume in humans and rats. Neurogastroenterol Motil. 2014 Jul;26(7):999-1009. [7]. Shimomura A, et al. Dietary L-lysineprevents arterial calcification in adenine-induced uremic rats. J Am Soc Nephrol. 2014 Sep;25(9):1954-65. [8]. Shimomura A, et al. Dietary L-lysineprevents arterial calcification in adenine-induced uremic rats. J Am Soc Nephrol. 2014 Sep;25(9):1954-65. [9]. Baruffol C, et al. L-lysine dose dependently delays gastric emptying and increases intestinal fluid volume in humans and rats. Neurogastroenterol Motil. 2014 Jul;26(7):999-1009. [10]. Baruffol C, et al. L-lysine dose dependently delays gastric emptying and increases intestinal fluid volume in humans and rats. Neurogastroenterol Motil. 2014 Jul;26(7):999-1009. |
Chemical & Physical Properties
| Melting Point | 263-264ºC (dec.)(lit.) |
|---|---|
| Molecular Formula | C6H7ClD8N2O2 |
| Molecular Weight | 190.69800 |
| Exact Mass | 190.13200 |
| PSA | 89.34000 |
| LogP | 1.72990 |
| InChIKey | BVHLGVCQOALMSV-RLIARQKESA-N |
| SMILES | Cl.NCCCCC(N)C(=O)O |
Synonyms
| L-LYSINE-3,3,4,4,5,5,6,6-D8 HYDROCHLORIDE |
| L-Lysine-d8 HCl |
