Introduction：Basic information about CAS 5001-33-2|(±)-Metanephrine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (±)-Metanephrine |
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| CAS Number | 5001-33-2 | Molecular Weight | 197.231 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 378.8±42.0 °C at 760 mmHg |
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| Molecular Formula | C10H15NO3 | Melting Point | 180-182ºC |
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| MSDS | / | Flash Point | 182.9±27.9 °C |
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Names
| Name | 4-[1-hydroxy-2-(methylamino)ethyl]-2-methoxyphenol |
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| Synonym | More Synonyms |
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(±)-Metanephrine BiologicalActivity
| Description | Metanephrine is the O-methylated metabolite of epinephrine that can be used for the research of diagnosis of pheochromocytoma[1]. |
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| Related Catalog | Research Areas >>Cancer |
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| Target | Human Endogenous Metabolite |
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| In Vitro | Metanephrine inhibits MPP+ uptake into Caki-1 cells and rat hepatocytes with IC50s of 34.2 µM and 302.0 µM, respectively[2]. |
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| References | [1]. Eisenhofer G, et al. Measurements of plasma methoxytyramine, normetanephrine, and metanephrine as discriminators of different hereditary forms of pheochromocytoma. Clin Chem. 2011 Mar;57(3):411-20. [2]. Martel F, et al. Comparison between uptake2 and rOCT1: effects of catecholamines, metanephrines and corticosterone. Naunyn Schmiedebergs Arch Pharmacol. 1999 Apr;359(4):303-9. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 378.8±42.0 °C at 760 mmHg |
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| Melting Point | 180-182ºC |
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| Molecular Formula | C10H15NO3 |
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| Molecular Weight | 197.231 |
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| Flash Point | 182.9±27.9 °C |
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| Exact Mass | 197.105194 |
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| PSA | 61.72000 |
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| LogP | -0.32 |
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| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
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| Index of Refraction | 1.557 |
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| InChIKey | JWJCTZKFYGDABJ-UHFFFAOYSA-N |
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| SMILES | CNCC(O)c1ccc(O)c(OC)c1 |
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Synonyms
| Metanephrine |
| DL-3-O-Methyladrenaline |
| 3-O-Methylepinephrine |
| DL-methanephrine |
| 4-Hydroxy-3-methoxy-a-(methylaminomethyl)benzenemethanol |
| 3-O-methyl-Adrenaline |
| 3-O-Methyladrenaline |
| DL-Metanephrine |
| 1-(4-Hydroxy-3-melhoxyphenyl)-2-methylaminoethanol |
| Benzenemethanol, 4-hydroxy-3-methoxy-α-((methylamino)methyl)- |
| 3-Methoxyadrenaline |
| metadrenaline |
| 4-[1-Hydroxy-2-(methylamino)ethyl]-2-methoxyphenol |
| a-(Methylaminomethyl)vanillyl Alcohol |
| m-O-Methyladrenaline |
| Benzenemethanol, 4-hydroxy-3-methoxy-α-[(methylamino)methyl]- |
| methyladrenaline |
