Introduction：Basic information about CAS 344299-49-6|1-Methylhistamine-d3 dihydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 1-Methylhistamine-d3 dihydrochloride |
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| CAS Number | 344299-49-6 | Molecular Weight | 201.11200 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C6H10Cl2D3N3 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | n-tau-methyl-d3-histamine 2hcl |
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| Synonym | More Synonyms |
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1-Methylhistamine-d3 dihydrochloride BiologicalActivity
| Description | 1-Methylhistamine-d3 (dihydrochloride) is the deuterium labeled 1-Methylhistamine (dihydrochloride)[1]. 1-Methylhistamine dihydrochloride is a histamine metabolite[2]. |
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| Related Catalog | Research Areas >>Metabolic Disease |
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| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
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| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Saito K, et al. Determination of urinary excretion of histamine and 1-methylhistamine by liquid chromatography. J Chromatogr B Biomed Appl. 1994 Apr 1;654(2):270-5. |
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Chemical & Physical Properties
| Molecular Formula | C6H10Cl2D3N3 |
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| Molecular Weight | 201.11200 |
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| Exact Mass | 200.06700 |
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| PSA | 43.84000 |
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| LogP | 2.22560 |
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| InChIKey | AGXVEALMQHTMSW-GXXYEPOPSA-N |
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| SMILES | Cl.Cl.Cn1cnc(CCN)c1 |
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Synonyms
| Nt-Methyl-d3-histaMine 2HCl |
| N-Methyl-D3-histamineHCl |
| NT-METHYL-D3-HISTAMINE DIHYDROCHLORIDE |
| N'-Methyl-D3-histamine2HCl |
