CAS 34592-47-7|L-Thioproline
Introduction：Basic information about CAS 34592-47-7|L-Thioproline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | L-Thioproline | ||
|---|---|---|---|
| CAS Number | 34592-47-7 | Molecular Weight | 133.169 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 350.3±37.0 °C at 760 mmHg |
| Molecular Formula | C4H7NO2S | Melting Point | 190-200 °C (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | 165.7±26.5 °C |
| Symbol | GHS06 | Signal Word | Danger |
Names
| Name | L-Thioproline |
|---|---|
| Synonym | More Synonyms |
L-Thioproline BiologicalActivity
| Description | (R)-Thiazolidine-4-carboxylic acid is a proline derivative[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| In Vitro | Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1]. |
| References | [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 350.3±37.0 °C at 760 mmHg |
| Melting Point | 190-200 °C (dec.)(lit.) |
| Molecular Formula | C4H7NO2S |
| Molecular Weight | 133.169 |
| Flash Point | 165.7±26.5 °C |
| Exact Mass | 133.019745 |
| PSA | 74.63000 |
| LogP | -0.39 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.566 |
| InChIKey | DZLNHFMRPBPULJ-VKHMYHEASA-N |
| SMILES | O=C(O)C1CSCN1 |
| Water Solubility | 28.5 g/L (20 ºC) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 210 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2547728
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 178 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00644
Safety Information
| Symbol | GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H312-H315-H319-H332-H335 |
| Precautionary Statements | P261-P280-P301 + P310-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R22 |
| Safety Phrases | S26-S36/37/39-S36 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | XJ5425500 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
| HS Code | 29341000 |
Customs
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles27
More Articles| Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1). Bioorg. Med. Chem. 19 , 6409-18, (2011) The proton-coupled amino acid transporter hPAT1 has recently gained much interest due to its ability to transport small drugs thereby allowing their oral administration. A three-dimensional quantitati... | |
| Design, synthesis and biological evaluation of 2-(substituted phenyl)thiazolidine-4-carboxylic acid derivatives as novel tyrosinase inhibitors. Biochimie 94(2) , 533-40, (2012) Herein we describe the design, synthesis and biological activities of 2-(substituted phenyl)thiazolidine-4-carboxylic acid derivatives as novel tyrosinase inhibitors. The target compounds 2a-2j were d... | |
| Successful computer guided planned synthesis of (4R)-thiazolidine carboxylic acid and its 2-substituted analogues as urease inhibitors. Mol. Divers. 10(2) , 223-31, (2006) By using internal combinatorial library we were able to identify (4R)-thiazolidines carboxylic acid and its 2-substituted analogs as active inhibitors of urease. Molecular modeling and virtual screeni... |
Synonyms
| H-THZ-OH |
| L-Thiazolidine-4-car |
| (R)-4-Thiazolidinecarboxylic acid |
| EINECS 252-106-3 |
| L-THC |
| THIAPROLINE |
| (4R)-4-Thiazolidinecarboxylic acid |
| (4R)-thiazolidine-4-carboxylic acid |
| 1,3-Thiazolidine-2-carboxylic acid |
| Thiazolidinecarboxylic acid (VAN) |
| THIAZOLIDINECARBOXYLIC ACID |
| 2-Thiazolidinecarboxylic acid |
| DL-Thiazolidinecarboxylic acid |
| L(-)-Thiazolidine-4-carboxylicacid |
| L(-)-Thiazolidine-4-Carboxylic Acid |
| L-Thiazolidine-4-carboxylic acid |
| H-L-THZ-OH |
| MFCD00005212 |
| (4R)-1,3-Thiazolidine-4-carboxylic acid |
| L-4-Thiazolidinecarboxylic acid |
| L-Thioproline |
| thiazolidinecarboxylicacid |
| (R)-(-)-4-Thiazolidinecarboxylic acid |
| L- thiazolidine-4-carboxylic acid |
| THIOPROLINE |
| H-THIOPRO-OH |
| L-THIAPROLINE |
| (R)-Thiazolidine-4-carboxylic acid |
| (R)-(-)-Thiazolidine-4-carboxylic Acid |
| L-thiazoline-4-carboxylic acid |
| 4-Thiazolidinecarboxylic acid, (4R)- |
