CAS 82-28-0|1-Amino-2-methyl-anthraquinone

Introduction：Basic information about CAS 82-28-0|1-Amino-2-methyl-anthraquinone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles5
7. Synonyms

Common Name	1-Amino-2-methyl-anthraquinone
CAS Number	82-28-0	Molecular Weight	237.253
Density	1.3±0.1 g/cm3	Boiling Point	481.1±45.0 °C at 760 mmHg
Molecular Formula	C₁₅H₁₁NO₂	Melting Point	204-206 °C(lit.)
MSDS	USA	Flash Point	244.8±28.7 °C

Names

Name	Disperse Orange 11
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	481.1±45.0 °C at 760 mmHg
Melting Point	204-206 °C(lit.)
Molecular Formula	C₁₅H₁₁NO₂
Molecular Weight	237.253
Flash Point	244.8±28.7 °C
Exact Mass	237.078979
PSA	60.16000
LogP	3.81
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.688
InChIKey	ZLCUIOWQYBYEBG-UHFFFAOYSA-N
SMILES	Cc1ccc2c(c1N)C(=O)c1ccccc1C2=O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CB5740000

CHEMICAL NAME :: Anthraquinone, 1-amino-2-methyl-

CAS REGISTRY NUMBER :: 82-28-0

BEILSTEIN REFERENCE NO. :: 0650595

LAST UPDATED :: 199701

DATA ITEMS CITED :: 15

MOLECULAR FORMULA :: C15-H11-N-O2

MOLECULAR WEIGHT :: 237.27

WISWESSER LINE NOTATION :: L C666 BV IVJ DZ E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 30 gm/kg/78W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 37 gm/kg/73W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 60 gm/kg/78W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 39 gm/kg/77W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 307 gm/kg/73W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 557 gm/kg/79W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1113 gm/kg/79W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 33 ug/plate

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11(Suppl 12),1,1988 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,199,1982 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,199,1982 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	CB5740000
HS Code	2922399090

Customs

HS Code	2922399090
Summary	2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles5

1-Amino-2-methylanthraquinone.

IARC Monogr. Eval. Carcinog. Risk Chem. Hum. 27 , 199-204, (1982)

1-Amino-2-methylanthraquinone.

Rep. Carcinog. 12 , 41, (2011)

1-Amino-2-methylanthraquinone.

Rep. Carcinog. 11 , III16, (2004)

Synonyms

1-Amino-2-methyl-anthraquinone

1-amino-2-methylanthracene-9,10-dione

1-Amino-2-methylanthraquinone (C.I. 60700)

MFCD00001220

EINECS 201-408-3

1-Amino-2-methyl-9,10-anthraquinone

9,10-Anthracenedione, 1-amino-2-methyl-

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