Introduction：Basic information about CAS 185428-18-6|Rivoglitazone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Rivoglitazone |
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| CAS Number | 185428-18-6 | Molecular Weight | 397.448 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 669.3±40.0 °C at 760 mmHg |
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| Molecular Formula | C20H19N3O4S | Melting Point | / |
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| MSDS | / | Flash Point | 358.6±27.3 °C |
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Names
| Name | 5-[[4-[(6-methoxy-1-methylbenzimidazol-2-yl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione |
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| Synonym | More Synonyms |
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Rivoglitazone BiologicalActivity
| Description | Rivoglitazone is a thiazolidinedione-derivative PPARγ agonist for the treatment of type 2 diabetes mellitus. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>PPARResearch Areas >>Metabolic Disease |
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| References | [1]. Kanda S, Nakashima R, Takahashi K, et al. Potent antidiabetic effects of rivoglitazone, a novel peroxisome proliferator-activated receptor-gamma agonist, in obese diabetic rodent models. J Pharmacol Sci. 2009;111(2):155-166. [2]. Uchiyama M, Iwabuchi H, Tsuruta F, et al. Pharmacokinetics, metabolism, and disposition of rivoglitazone, a novel peroxisome proliferator-activated receptor γ agonist, in rats and monkeys. Drug Metab Dispos. 2011;39(4):653-666. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 669.3±40.0 °C at 760 mmHg |
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| Molecular Formula | C20H19N3O4S |
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| Molecular Weight | 397.448 |
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| Flash Point | 358.6±27.3 °C |
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| Exact Mass | 397.109619 |
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| PSA | 107.75000 |
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| LogP | 2.95 |
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| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
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| Index of Refraction | 1.683 |
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| InChIKey | XMSXOLDPMGMWTH-UHFFFAOYSA-N |
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| SMILES | COc1ccc2nc(COc3ccc(CC4SC(=O)NC4=O)cc3)n(C)c2c1 |
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Synonyms
| Rivoglitazone |
| 2,4-Thiazolidinedione, 5-[[4-[(6-methoxy-1-methyl-1H-benzimidazol-2-yl)methoxy]phenyl]methyl]- |
| Rivoglitazone [USAN] |
| 5-{4-[(6-Methoxy-1-methyl-1H-benzimidazol-2-yl)methoxy]benzyl}-1,3-thiazolidine-2,4-dione |
| UNII:3A3N0634Q6 |
| Rivoglitazone [USAN:INN] |
| 5-[4-(6-Methoxy-1-methylbenzimidazol-2-yl-methoxy)benzyl]-thiazolidine-2,4-dione |
| (5R)-5-{4-[(6-methoxy-1-methyl-1H-benzimidazol-2-yl)methoxy]benzyl}1,3-thiazolidine-2,4-dione |
| UNII-3A3N0634Q6 |
| 5-[4-(6-methoxy-1-methyl-1H-benzimidazol-2-ylmethoxy)benzyl] thiazolidine-2,4-dione |
| (5-[4-(6-methoxy-1-methyl-1H-benzimidazol-2-ylmethoxy)benzyl]thiazolidin-2,4-dione) |
