CAS 1852-49-9|Pregnanediol 3-glucuronide
| Common Name | Pregnanediol 3-glucuronide | ||
|---|---|---|---|
| CAS Number | 1852-49-9 | Molecular Weight | 496.63300 |
| Density | 1.3g/cm3 | Boiling Point | 666.4ºC at 760mmHg |
| Molecular Formula | C27H44O8 | Melting Point | >94°C (dec.) (lit.) |
| MSDS | USA | Flash Point | 217.2ºC |
Names
| Name | Pregnanediol 3α-O-β-D-Glucuronide |
|---|---|
| Synonym | More Synonyms |
Pregnanediol 3-glucuronide BiologicalActivity
| Description | Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone, playing an important role in physiological processes, such as the female menstrual cycle, pregnancy (supports gestation), embryogenesis and maternal immune response of humans and other species[1]. |
|---|---|
| Related Catalog | Research Areas >>Endocrinology |
| Target | Human Endogenous Metabolite |
| References | [1]. Chen J, et al. Quantitation of serum pregnanediol-3-glucuronide level in different endocrine statuses by LC-MS/MS. J Pharm Biomed Anal. 2020;184:113171. |
Chemical & Physical Properties
| Density | 1.3g/cm3 |
|---|---|
| Boiling Point | 666.4ºC at 760mmHg |
| Melting Point | >94°C (dec.) (lit.) |
| Molecular Formula | C27H44O8 |
| Molecular Weight | 496.63300 |
| Flash Point | 217.2ºC |
| Exact Mass | 496.30400 |
| PSA | 136.68000 |
| LogP | 2.30350 |
| Vapour Pressure | 1.34E-20mmHg at 25°C |
| Index of Refraction | 1.587 |
| InChIKey | ZFFFJLDTCLJDHL-IUGLSFICSA-N |
| SMILES | CC(O)C1CCC2C3CCC4CC(OC5OC(C(=O)O)C(O)C(O)C5O)CCC4(C)C3CCC12C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles25
More Articles| Progesterone, pregnanediol-3-glucuronide, relaxin and oestrone sulphate concentrations in saliva, milk and urine of female alpacas (Vicugna pacos) and their application in pregnancy diagnosis. Vet. Rec. 171(8) , 195, (2012) The pregnancy-associated hormones, progesterone (P4), pregnanediol-3-glucuronide (PdG), relaxin (RLN) and oestrone sulphate (E1S) in plasma, saliva, milk and urine of alpacas were measured in order to... | |
| Factors related to declining luteal function in women during the menopausal transition. J. Clin. Endocrinol. Metab. 93(5) , 1711-21, (2008) Reproductive hormones are incompletely characterized during the menopause transition (MT).Increased anovulation and decreased progesterone accompany progress through the MT.The Daily Hormone Study (DH... | |
| Describing ovarian cycles, pregnancy characteristics, and the use of contraception in female white-faced marmosets, Callithrix geoffroyi. Am. J. Primatol. 74(11) , 1044-53, (2012) Endocrine data and characteristics of nonconceptive ovarian cycling and pregnancy are limited within the genus Callithrix to the common marmoset (C. jacchus) and Wied's black tufted-ear marmoset (C. k... |
Synonyms
| 3alpha,20alpha-dihydroxy-5beta-pregnane 3-glucuronide |
