Introduction：Basic information about CAS 63644-62-2|Coniferyl ferulate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Coniferyl ferulate |
|---|
| CAS Number | 63644-62-2 | Molecular Weight | 356.369 |
|---|
| Density | 1.3±0.1 g/cm3 | Boiling Point | 570.5±50.0 °C at 760 mmHg |
|---|
| Molecular Formula | C20H20O6 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 202.8±23.6 °C |
|---|
Names
| Name | 3-(4-Hydroxy-3-methoxyphenyl)allyl 3-(4-hydroxy-3-methoxyphenyl)acrylate |
|---|
| Synonym | More Synonyms |
|---|
Coniferyl ferulate BiologicalActivity
| Description | Coniferyl ferulate, a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis, reverses multidrug resistance and downregulates P-glycoprotein. Coniferyl ferulate shows strong inhibition of human placental GST with an IC50 of 0.3 μM[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Metabolic Enzyme/Protease >>Gutathione S-transferaseSignaling Pathways >>Membrane Transporter/Ion Channel >>P-glycoprotein |
|---|
| Target | Glutathione S-transferase[1] P-glycoprotein[1] |
|---|
| References | [1]. Chen C, et al. Coniferyl Ferulate, a Strong Inhibitor of Glutathione S-Transferase Isolated from Radix Angelicae sinensis, Reverses Multidrug Resistance and Downregulates P-Glycoprotein. Evid Based Complement Alternat Med. 2013;2013:639083. |
|---|
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|
| Boiling Point | 570.5±50.0 °C at 760 mmHg |
|---|
| Molecular Formula | C20H20O6 |
|---|
| Molecular Weight | 356.369 |
|---|
| Flash Point | 202.8±23.6 °C |
|---|
| Exact Mass | 356.125977 |
|---|
| PSA | 85.22000 |
|---|
| LogP | 2.78 |
|---|
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
|---|
| Index of Refraction | 1.640 |
|---|
| InChIKey | PGLIMMMHQDNVRS-YZQQHVNFSA-N |
|---|
| SMILES | COc1cc(C=CCOC(=O)C=Cc2ccc(O)c(OC)c2)ccc1O |
|---|
| Storage condition | 2-8C |
|---|
Safety Information
Customs
| HS Code | 2918990090 |
|---|
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
|---|
Synonyms
| (2E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propen-1-yl (2E)-3-(4-hydroxy-3-methoxyphenyl)acrylate |
| 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, (2E)-3-(4-hydroxy-3-methoxyphenyl)-2-propen-1-yl ester, (2E)- |
| [(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enyl] (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate |
| 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, 3-(4-hydroxy-3-methoxyphenyl)-2-propenyl ester |
