CAS 97-52-9|4-Nitro-o-anisidine

Introduction：Basic information about CAS 97-52-9|4-Nitro-o-anisidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles3
7. Synonyms

Common Name	4-Nitro-o-anisidine
CAS Number	97-52-9	Molecular Weight	168.150
Density	1.3±0.1 g/cm3	Boiling Point	364.2±22.0 °C at 760 mmHg
Molecular Formula	C₇H₈N₂O₃	Melting Point	140-142 °C(lit.)
MSDS	ChineseUSA	Flash Point	174.0±22.3 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	2-Methoxy-4-nitroaniline
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	364.2±22.0 °C at 760 mmHg
Melting Point	140-142 °C(lit.)
Molecular Formula	C₇H₈N₂O₃
Molecular Weight	168.150
Flash Point	174.0±22.3 °C
Exact Mass	168.053497
PSA	81.07000
LogP	1.85
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.601
InChIKey	GVBHRNIWBGTNQA-UHFFFAOYSA-N
SMILES	COc1cc([N+](=O)[O-])ccc1N
Water Solubility	slightly soluble

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ7170000

CHEMICAL NAME :: o-Anisidine, 4-nitro-

CAS REGISTRY NUMBER :: 97-52-9

BEILSTEIN REFERENCE NO. :: 0879619

LAST UPDATED :: 199710

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C7-H8-N2-O3

MOLECULAR WEIGHT :: 168.17

WISWESSER LINE NOTATION :: WNR DZ C01

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 997 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,717,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0147 No. of Facilities: 174 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 523 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0147 No. of Facilities: 70 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 198 (estimated) No. of Female Employees: 80 (estimated)

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R20/21/22
Safety Phrases	S26-S37/39-S36/37
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	BZ7170000
Hazard Class	6.1
HS Code	29222900

Customs

HS Code	2922299090
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles3

2-Methoxy-4-nitroaniline is a selective inducer of cytochrome P450IA2 (CYP1A2) in rat liver.

Cancer Lett. 96(1) , 95-8, (1995)

Male F344 rats were treated with a chemical (aniline, nitrobenzene, 2-methoxy-p-phenylenediamine, 2-methoxy-4-nitroaniline or 2-methoxy-4-nitroazobenzene) produced by the azo-reduction and/or N-oxidat...

Metabolism and disposition of 2-methoxy-4-nitroaniline in male and female Harlan Sprague Dawley rats and B6C3F1/N mice.

Xenobiotica 42(12) , 1213-24, (2012)

The disposition of 2-Methoxy-4-nitroaniline (MNA) was investigated in male and female Harlan Sprague Dawley rats and B6C3F(1)/N mice following oral, intravenous, and dermal exposure to [(14)C]MNA at 2...

Use of nitroanilines for spectrophotometric determination of ethinylestradiol in pharmaceutical formulations. Leonardo SG, et al.

Anal. Methods 3(5) , 1198-1201, (2011)

Synonyms

2-METHOXY-4-NITROANILINE/4-NITRO-O-ANISIDINE

EINECS 202-588-6

2-Amino-5-nitroanisole

2-amino-5-nitroanisol

2-methoxy-4nitro-aniline

4-Nitro-o-anisidine

KERNECHTROT SALT B

2-Methoxy-4-nitrobenzenamine

2-METHOXY-4-NITRO-ANILINE 97-52-9

2-Methoxy-4-nitroaniline

2-METHOXY-4-NITROANILINE FOR SYNTHESIS

Red B Base

2-methoxy-4-nitrophenylamine

1-amino-2-methoxy-4-nitrobenzene

Fast Red B

2-Amino-1-methoxy-5-nitrobenzene

2-METHOXY-4-NITROANILIN

4-Nitro-6-methoxyaniline

Benzenamine, 2-methoxy-4-nitro-

5-nitro-2-amino-1-methoxy-benzene

Fast Red Base B

Benzenamine,2-methoxy-4-nitro

o-Anisidine,4-nitro

2-METHOXY-4-NITRO ANILINE

5-Nitro-2-anisidine

5-nitro-2-amino-anisole

MFCD00007363

4-Amino-3-methoxynitrobenzene

4-NITRO-O-ANISIDINE (NH2=1)

Fast Red B Base

FASTREDBBASE

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