Introduction：Basic information about CAS 172531-37-2|2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetic acid |
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| CAS Number | 172531-37-2 | Molecular Weight | 233.22200 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C8H15N3O5 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 11-Azido-3,6,9-trioxaundecanoic Acid |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | PROTAC Linker 14 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 14 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | Alkyl/ether |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
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Chemical & Physical Properties
| Molecular Formula | C8H15N3O5 |
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| Molecular Weight | 233.22200 |
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| Exact Mass | 233.10100 |
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| PSA | 114.74000 |
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| Index of Refraction | 1.47 |
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| InChIKey | GIXBCECBLAEYKA-UHFFFAOYSA-N |
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| SMILES | [N-]=[N+]=NCCOCCOCCOCC(=O)O |
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Synonyms
| Azido-PEG3-carboxylate |
| 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetic acid |
