Introduction：Basic information about CAS 5633-14-7|Benzetimide hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Benzetimide hydrochloride |
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| CAS Number | 5633-14-7 | Molecular Weight | 398.926 |
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| Density | / | Boiling Point | 543.9ºC at 760 mmHg |
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| Molecular Formula | C23H27ClN2O2 | Melting Point | / |
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| MSDS | / | Flash Point | 282.7ºC |
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Names
| Name | 3-(1-benzylpiperidin-4-yl)-3-phenylpiperidine-2,6-dione,hydrochloride |
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| Synonym | More Synonyms |
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Benzetimide hydrochloride BiologicalActivity
| Description | Benzetimide hydrochloride is a muscarinic acetylcholine receptor antagonist. Target: mAChR |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>mAChRSignaling Pathways >>Neuronal Signaling >>mAChRResearch Areas >>Neurological Disease |
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Chemical & Physical Properties
| Boiling Point | 543.9ºC at 760 mmHg |
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| Molecular Formula | C23H27ClN2O2 |
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| Molecular Weight | 398.926 |
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| Flash Point | 282.7ºC |
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| Exact Mass | 398.176117 |
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| PSA | 52.90000 |
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| LogP | 4.28900 |
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| InChIKey | XSOOSXRNMDUWEM-UHFFFAOYSA-N |
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| SMILES | Cl.O=C1CCC(c2ccccc2)(C2CCN(Cc3ccccc3)CC2)C(=O)N1 |
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| Storage condition | 2-8℃ |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- MA4030000
- CHEMICAL NAME :
- Glutarimide, 2-(1-benzyl-4-piperidyl)-2-phenyl-, hydrochloride
- CAS REGISTRY NUMBER :
- 5633-14-7
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C23-H26-N2-O2.Cl-H
- MOLECULAR WEIGHT :
- 398.97
- WISWESSER LINE NOTATION :
- T6VMVTJ DR& D- DT6NTJ A1R &GH
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 37600 ug/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 21,1365,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 680 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,283,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 46 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 21,1365,1971
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Safety Information
| Hazard Codes | Xn |
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| Risk Phrases | 22 |
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| RIDADR | UN 3249 |
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| Packaging Group | III |
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| Hazard Class | 6.1(b) |
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Synonyms
| Dioxatrine |
| 1'-Benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione hydrochloride (1:1) |
| Spasmentral |
| R 4929 |
| Benzetimide HCl |
| EINECS 227-072-8 |
| [3,4'-Bipiperidine]-2,6-dione, 3-phenyl-1'-(phenylmethyl)-, hydrochloride (1:1) |
| McN-JR4929 |
| BENZETIMIDE HYDROCHLORIDE |
| Benzetimide (hydrochloride) |
