Introduction：Basic information about CAS 82-88-2|phenindamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | phenindamine |
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| CAS Number | 82-88-2 | Molecular Weight | 261.36100 |
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| Density | 1.15g/cm3 | Boiling Point | 416.5ºC at 760 mmHg |
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| Molecular Formula | C19H19N | Melting Point | 90-91° |
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| MSDS | / | Flash Point | 183ºC |
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Names
| Name | 2-methyl-9-phenyl-1,3,4,9-tetrahydroindeno[2,1-c]pyridine |
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| Synonym | More Synonyms |
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phenindamine BiologicalActivity
| Description | Phenindamine (Nu 1504) is an antihistamine[1]. |
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| Related Catalog | Signaling Pathways >>Immunology/Inflammation >>Histamine ReceptorResearch Areas >>Neurological DiseaseSignaling Pathways >>GPCR/G Protein >>Histamine Receptor |
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| In Vivo | Phenindamine (2-10 mg/kg; i.p.; once) shows performance enhancement effect in rats[1]. Animal Model: Adult male Long-Evans strain rats[1] Dosage: 2, 5 and 10 mg/kg Administration: Intraperitoneal injection, once Result: Decreased attention index (AI) and increase the AI variance. Produced a dose-related increase in the performance index (PI). |
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Chemical & Physical Properties
| Density | 1.15g/cm3 |
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| Boiling Point | 416.5ºC at 760 mmHg |
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| Melting Point | 90-91° |
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| Molecular Formula | C19H19N |
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| Molecular Weight | 261.36100 |
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| Flash Point | 183ºC |
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| Exact Mass | 261.15200 |
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| PSA | 3.24000 |
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| LogP | 3.85910 |
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| Index of Refraction | 1.652 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- NK9460500
- CHEMICAL NAME :
- 1H-Indeno(2,1-c)pyridine, 2,3,4,9-tetrahydro-2-methyl-9-phenyl-
- CAS REGISTRY NUMBER :
- 82-88-2
- BEILSTEIN REFERENCE NO. :
- 0221083
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C19-H19-N
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 129 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 124,350,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 265 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 188,271,1970
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Synonyms
| Fenindamina |
| Phenindamine (INN) |
| Phenindamine [INN:BAN] |
| Phenindaminum |
| 2-methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-c]pyridine |
| Nolahist |
| 2-Methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-c]pyridin |
| Phenindiamine |
| Phenindamin |
| Phenindaminum [INN-Latin] |
| Fenindamina [INN-Spanish] |
| Thephorin |
| Phenindamine |
