Introduction：Basic information about CAS 1830-32-6|azintamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | azintamide |
|---|
| CAS Number | 1830-32-6 | Molecular Weight | 259.76 |
|---|
| Density | 1.27g/cm3 | Boiling Point | 435.3ºC at 760 mmHg |
|---|
| Molecular Formula | C10H14ClN3OS | Melting Point | 97ºC |
|---|
| MSDS | / | Flash Point | 217ºC |
|---|
Names
| Name | 2-(6-chloropyridazin-3-yl)sulfanyl-N,N-diethylacetamide |
|---|
| Synonym | More Synonyms |
|---|
azintamide BiologicalActivity
| Description | Azintamide (Bilipurum) can be used for the research of psoriasis vulgaris, dyspepsia and other conditions[1][2]. |
|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
|---|
| References | [1]. Zhu L, et, al. [Efficacy and safety of compound azintamide on dyspepsia symptoms in a multicentre self-controlled trial]. Zhonghua Nei Ke Za Zhi. 2008 Nov;47(11):910-3. [2]. Diezel W, et, al. [Azintamid as a therapeutic agent in psoriasis vulgaris - a therapeutic study]. Dermatol Monatsschr. 1983;169(8):521-4. |
|---|
Chemical & Physical Properties
| Density | 1.27g/cm3 |
|---|
| Boiling Point | 435.3ºC at 760 mmHg |
|---|
| Melting Point | 97ºC |
|---|
| Molecular Formula | C10H14ClN3OS |
|---|
| Molecular Weight | 259.76 |
|---|
| Flash Point | 217ºC |
|---|
| Exact Mass | 259.05500 |
|---|
| PSA | 71.39000 |
|---|
| LogP | 2.09050 |
|---|
| Vapour Pressure | 8.88E-08mmHg at 25°C |
|---|
| Index of Refraction | 1.573 |
|---|
| InChIKey | SSLKKMZJCJBOML-UHFFFAOYSA-N |
|---|
| SMILES | CCN(CC)C(=O)CSc1ccc(Cl)nn1 |
|---|
Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- AB5836500
- CHEMICAL NAME :
- Acetamide, 2-((6-chloro-3-pyridazinyl)thio)-N,N-diethyl-
- CAS REGISTRY NUMBER :
- 1830-32-6
- BEILSTEIN REFERENCE NO. :
- 0885011
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C10-H14-Cl-N3-O-S
- MOLECULAR WEIGHT :
- 259.78
- WISWESSER LINE NOTATION :
- T6NNJ CG FS1VN2&2
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1550 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,266,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 540 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,111,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1150 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,111,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,111,1974
|
Synonyms
| Oragallin |
| Azinthiamide |
| Oragal |
| Oragalin |
| Oragallin purum |
| Biloral |
| Azintamid |
| Bilipurum |
| Colerin |
| Azintamide |
