Introduction：Basic information about CAS 64840-90-0|Eperisone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Eperisone |
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| CAS Number | 64840-90-0 | Molecular Weight | 259.38600 |
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| Density | 0.994 g/cm3 | Boiling Point | 386.8ºC at 760 mmHg |
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| Molecular Formula | C17H25NO | Melting Point | 170-172ºC |
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| MSDS | / | Flash Point | 137.4ºC |
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Names
| Name | 1-(4-ethylphenyl)-2-methyl-3-piperidin-1-ylpropan-1-one |
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| Synonym | More Synonyms |
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Eperisone BiologicalActivity
| Description | Eperisone is an antispastic agent used for treatment of diseases characterized by muscle stiffness and pain. It works by relaxing both skeletal muscles and vascularsmooth muscles, thus demonstrating avariety of effects such as reduction ofmyotonia, improvement of circulationand suppression of the pain reflex. Eperisone is a centrally acting muscle relaxant inhibiting the pain reflex pathway, having a vasodilator effect[1][2 [3]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
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| References | [1]. Cabitza P, et al. Efficacy and safety of eperisone in patients with low back pain: a double blind randomized study. Eur Rev Med Pharmacol Sci. 2008 Jul-Aug;12(4):229-35. [2]. Frandisco Colomer Rusinvol, et al. Effects of Two Diffferent Doses of Eperisone in the Treatment of Acute Low Back Pain. The Journal of Applied Research. [3]. Bavage S, et al. Clinical efficacy and safety of eperisone for low back pain: A systematic literature review. Pharmacol Rep. 2016 Oct;68(5):903-12. |
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Chemical & Physical Properties
| Density | 0.994 g/cm3 |
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| Boiling Point | 386.8ºC at 760 mmHg |
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| Melting Point | 170-172ºC |
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| Molecular Formula | C17H25NO |
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| Molecular Weight | 259.38600 |
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| Flash Point | 137.4ºC |
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| Exact Mass | 259.19400 |
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| PSA | 20.31000 |
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| LogP | 3.49160 |
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| InChIKey | SQUNAWUMZGQQJD-UHFFFAOYSA-N |
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| SMILES | CCc1ccc(C(=O)C(C)CN2CCCCC2)cc1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- UC2022000
- CHEMICAL NAME :
- 1-Propanone, 1-(4-ethylphenyl)-2-methyl-3-(1-piperidinyl)-
- CAS REGISTRY NUMBER :
- 64840-90-0
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C17-H25-N-O
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 4550 mg/kg/13W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Endocrine - changes in adrenal weight
- REFERENCE :
- YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 20,1027,1992
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Safety Information
Customs
| HS Code | 2933399090 |
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| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 4-ethylphenyl-2-methyl-3-piperidinopropiopenone |
| 4'-ethyl-2-methyl-3-piperidino-propiophenone |
| EMPP |
| eperisone |
| MFCD00867679 |
| Eperisone HCl |
