Introduction：Basic information about CAS 71142-71-7|H-D-Phe-Pro-Arg-chloromethylketone trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | H-D-Phe-Pro-Arg-chloromethylketone trifluoroacetate salt |
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| CAS Number | 71142-71-7 | Molecular Weight | 450.96 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C21H31ClN6O3 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | H-D-Phe-Pro-Arg-chloromethylketone |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | PPACK is a plasminogen activator (rt-PA) inhibitor. PPACK can inhibit changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin. PPACK also inhibits the binding of rt-PA to plasma protease inhibitors[1]. |
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| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>PAI-1Research Areas >>Cardiovascular Disease |
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| References | [1]. Mohler MA, et, al. D-Phe-Pro-Arg-chloromethylketone: its potential use in inhibiting the formation of in vitro artifacts in blood collected during tissue-type plasminogen activator thrombolytic therapy. Thromb Haemost. 1986 Oct 21;56(2):160-4. |
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Chemical & Physical Properties
| Molecular Formula | C21H31ClN6O3 |
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| Molecular Weight | 450.96 |
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| Exact Mass | 466.21000 |
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| PSA | 163.63000 |
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| LogP | 2.25500 |
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| InChIKey | KWPACVJPAFGBEQ-IKGGRYGDSA-N |
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| SMILES | NC(N)=NCCCC(NC(=O)C1CCCN1C(=O)C(N)Cc1ccccc1)C(=O)CCl |
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| Storage condition | -15°C |
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Synonyms
| H-D-PHE-PRO-ARG-CHLOROMETHYLKETONE TRIFLUOROACETATE SALT |
| phenylalanyl-prolyl-argininemethylchloride |
| H-D-PHE-PRO-ARG-CMK TFA |
