Introduction：Basic information about CAS 588691-24-1|5'-O-DMT-5-I-2'-OMe-rU, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5'-O-DMT-5-I-2'-OMe-rU |
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| CAS Number | 588691-24-1 | Molecular Weight | 686.49 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C31H31IN2O8 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-5-iodopyrimidine-2,4-dione |
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| Synonym | More Synonyms |
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5'-O-DMT-5-I-2'-OMe-rU BiologicalActivity
| Description | 2’-O-Methyl-5’-O-DMTr-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Molecular Formula | C31H31IN2O8 |
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| Molecular Weight | 686.49 |
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| Exact Mass | 686.11300 |
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| PSA | 121.24000 |
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| LogP | 3.44040 |
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| InChIKey | VYNNFLLSYDWMCJ-LTGLEFCMSA-N |
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| SMILES | COc1ccc(C(OCC2OC(n3cc(I)c(=O)[nH]c3=O)C(OC)C2O)(c2ccccc2)c2ccc(OC)cc2)cc1 |
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Synonyms
