Introduction：Basic information about CAS 475-80-9|Aristolochic acid B, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Aristolochic acid B |
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| CAS Number | 475-80-9 | Molecular Weight | 311.246 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | 592.2±50.0 °C at 760 mmHg |
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| Molecular Formula | C16H9NO6 | Melting Point | 270-272℃ |
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| MSDS | ChineseUSA | Flash Point | 311.9±30.1 °C |
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Names
| Name | Aristolochic acid B |
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| Synonym | More Synonyms |
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Aristolochic acid B BiologicalActivity
| Description | Aristolochic acid B is one of the major components of Aristolochic acids (AA) which are natural products derived from taxa in the Aristolochiaceae. Aristolochic acid is known to be a potent mutagen and carcinogen. Aristolochic acid B showes more carcinogenic risk than Aristolochic acid A in vivo[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| References | [1]. Xing G, et al. Comparison of the mutagenicity of aristolochic acid I and aristolochic acid II in the gpt delta transgenic mouse kidney. Mutat Res. 2012 Mar 18;743(1-2):52-8. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Boiling Point | 592.2±50.0 °C at 760 mmHg |
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| Melting Point | 270-272℃ |
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| Molecular Formula | C16H9NO6 |
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| Molecular Weight | 311.246 |
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| Flash Point | 311.9±30.1 °C |
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| Exact Mass | 311.042999 |
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| PSA | 101.58000 |
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| LogP | 3.50 |
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| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
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| Index of Refraction | 1.787 |
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| InChIKey | MEEXETVZNQYRSP-UHFFFAOYSA-N |
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| SMILES | O=C(O)c1cc2c(c3c1c([N+](=O)[O-])cc1ccccc13)OCO2 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- SF8281600
- CHEMICAL NAME :
- Phenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid, 6-nitro-
- CAS REGISTRY NUMBER :
- 475-80-9
- BEILSTEIN REFERENCE NO. :
- 0329754
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C16-H9-N-O6
- MOLECULAR WEIGHT :
- 311.26
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- DNA adduct
MUTATION DATA - TEST SYSTEM :
- Rodent - rat
- DOSE/DURATION :
- 128 ug/kg
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10,275,1987
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Safety Information
| RIDADR | UN 2811 |
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| Packaging Group | III |
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| Hazard Class | 6.1(b) |
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Synonyms
| 6-Nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid |
| 6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid |
| Aristolochic Acid B |
| Phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid, 6-nitro- |
| Aristolochic acid II |
