CAS 78-88-6|2,3-Dichloropropene
Introduction：Basic information about CAS 78-88-6|2,3-Dichloropropene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2,3-Dichloropropene | ||
|---|---|---|---|
| CAS Number | 78-88-6 | Molecular Weight | 110.97000 |
| Density | 1.204 g/mL at 25 °C(lit.) | Boiling Point | 94 °C(lit.) |
| Molecular Formula | C3H4Cl2 | Melting Point | 10°C |
| MSDS | ChineseUSA | Flash Point | 50 °F |
| Symbol | GHS02, GHS05, GHS07, GHS08 | Signal Word | Danger |
Names
| Name | 2,3-Dichloro-1-propene |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.204 g/mL at 25 °C(lit.) |
|---|---|
| Boiling Point | 94 °C(lit.) |
| Melting Point | 10°C |
| Molecular Formula | C3H4Cl2 |
| Molecular Weight | 110.97000 |
| Flash Point | 50 °F |
| Exact Mass | 109.96900 |
| LogP | 1.97770 |
| Vapour density | 3.8 (vs air) |
| Vapour Pressure | 44 mm Hg ( 20 °C) |
| Index of Refraction | n20/D 1.461(lit.) |
| InChIKey | FALCMQXTWHPRIH-UHFFFAOYSA-N |
| SMILES | C=C(Cl)CCl |
| Water Solubility | <0.1 g/100 mL at 22 ºC |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 320 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 ppm/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3100 mg/m3/2H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1580 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 300 umol/L
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9,401,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5383 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 7 No. of Employees: 302 (estimated) No. of Female Employees: 3 (estimated)
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 300 umol/L
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9,401,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5383 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 7 No. of Employees: 302 (estimated) No. of Female Employees: 3 (estimated)
Safety Information
| Symbol | GHS02, GHS05, GHS07, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H302-H312-H315-H318-H332-H335-H341-H412 |
| Precautionary Statements | P210-P261-P273-P280-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | F:Flammable |
| Risk Phrases | R11;R20/21/22;R37/38;R40;R41;R52/53 |
| Safety Phrases | S9-S16-S23-S26-S36/37/39-S61 |
| RIDADR | UN 2047 3/PG 2 |
| WGK Germany | 3 |
| RTECS | UC8400000 |
| Packaging Group | II |
| Hazard Class | 3 |
| HS Code | 29032900 |
Customs
| HS Code | 29032900 |
|---|
Articles9
More Articles| Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity. Bioorg. Med. Chem. 16 , 5720-32, (2008) The risk of the presence of haloacetic acids in drinking water as chlorination by-products and the shortage of experimental mutagenicity data for most of them requires a research work. This paper desc... | |
| Mutagenicity of chloroolefins in the Salmonella/mammalian microsome test. III. Metabolic activation of the allylic chloropropenes allyl chloride, 1,3-dichloropropene, 2,3-dichloro-1-propene, 1,2,3-trichloropropene, 1,1,2,3-tetrachloro-2-propene and hexachloropropene by S9 mix via two different metabolic pathways. Mutat. Res. 170(1-2) , 1-9, (1986) In the presence of S9 mix all allylic chloropropenes tested exert considerable indirect mutagenic activity which is most pronounced for 1,2,3-trichloropropene. Lower as well as higher chlorinated deri... | |
| Evidence for a radical mechanism of the dechlorination of chlorinated propenes mediated by the tetrachloroethene reductive dehalogenase of Sulfurospirillum muftivorans. Environ. Sci. Technol. 41(21) , 7370-5, (2007) The reductive dehalogenation of chlorinated propenes was studied with the tetrachloroethene reductive dehalogenase purified from Sulfurospirillum multivorans to obtain indications for a radical mechan... |
Synonyms
| MFCD00000943 |
| 2,3-dichloroprop-1-ene |
| EINECS 201-153-8 |
