CAS 78273-80-0|Roxatidine

Introduction：Basic information about CAS 78273-80-0|Roxatidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Roxatidine BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	Roxatidine
CAS Number	78273-80-0	Molecular Weight	306.40000
Density	1.137 g/cm3	Boiling Point	524.3ºC at 760 mmHg
Molecular Formula	C₁₇H₂₆N₂O₃	Melting Point	/
MSDS	/	Flash Point	270.9ºC

Names

Name	Roxatidine
Synonym	More Synonyms

Roxatidine BiologicalActivity

Description	Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is a histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect[1].
Related Catalog	Signaling Pathways >>Immunology/Inflammation >>Histamine ReceptorResearch Areas >>Inflammation/ImmunologySignaling Pathways >>GPCR/G Protein >>Histamine Receptor
References	[1]. Lee M, et al. Roxatidine attenuates mast cell-mediated allergic inflammation via inhibition of NF-κB and p38 MAPK activation. Sci Rep. 2017;7:41721. Published 2017 Jan 31.

Chemical & Physical Properties

Density	1.137 g/cm3
Boiling Point	524.3ºC at 760 mmHg
Molecular Formula	C₁₇H₂₆N₂O₃
Molecular Weight	306.40000
Flash Point	270.9ºC
Exact Mass	306.19400
PSA	61.80000
LogP	1.87870
InChIKey	BCCREUFCSIMJFS-UHFFFAOYSA-N
SMILES	O=C(CO)NCCCOc1cccc(CN2CCCCC2)c1

Safety Information

HS Code	2933399090

Customs

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

ROXATIDINE ENTERPRISE STANDARD

MFCD00871807

desacetyl-TZU-0460

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