CAS 18474-59-4|6-Methyl-1H-indole-2-carboxylic acid

Introduction：Basic information about CAS 18474-59-4|6-Methyl-1H-indole-2-carboxylic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 6-Methyl-1H-indole-2-carboxylic acid BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	6-Methyl-1H-indole-2-carboxylic acid
CAS Number	18474-59-4	Molecular Weight	175.184
Density	1.3±0.1 g/cm3	Boiling Point	411.5±25.0 °C at 760 mmHg
Molecular Formula	C₁₀H₉NO₂	Melting Point	220°C
MSDS	USA	Flash Point	202.7±23.2 °C

Names

Name	6-Methyl-1H-indole-2-carboxylic acid
Synonym	More Synonyms

6-Methyl-1H-indole-2-carboxylic acid BiologicalActivity

Description	eIF4A3-IN-8 is a selective ATP-competitive eukaryotic initiation factor 4A3 (eIF4A3) inhibitor. eIF4A3-IN-8 can serve as a valuable chemical probe to elucidate the detailed function of eIF4A3 and EJC (exon junction complex)[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Eukaryotic Initiation Factor (eIF)
References	[1]. Ito M, et al. Discovery of selective ATP-competitive eIF4A3 inhibitors. Bioorg Med Chem. 2017 Apr 1;25(7):2200-2209.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	411.5±25.0 °C at 760 mmHg
Melting Point	220°C
Molecular Formula	C₁₀H₉NO₂
Molecular Weight	175.184
Flash Point	202.7±23.2 °C
Exact Mass	175.063324
PSA	53.09000
LogP	2.77
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.696
InChIKey	ZKGSVVHFMZASJS-UHFFFAOYSA-N
SMILES	Cc1ccc2cc(C(=O)O)[nH]c2c1
Storage condition	2-8°C

Safety Information

Hazard Codes	Xi: Irritant;
HS Code	2933990090

Customs

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

1H-Indole-2-carboxylic acid, 6-methyl-

6-Methyl-1H-indole-2-carboxylic acid

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