Introduction：Basic information about CAS 33453-23-5|Ciproquazone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ciproquazone |
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| CAS Number | 33453-23-5 | Molecular Weight | 306.35800 |
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| Density | 1.26g/cm3 | Boiling Point | 483.8ºC at 760mmHg |
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| Molecular Formula | C19H18N2O2 | Melting Point | / |
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| MSDS | / | Flash Point | 246.4ºC |
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Names
| Name | 1-(cyclopropylmethyl)-6-methoxy-4-phenylquinazolin-2-one |
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| Synonym | More Synonyms |
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Ciproquazone BiologicalActivity
| Description | Ciproquazone has analgesic activity and is used to treat spondylitis. |
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| References | 1. Vega S, et al. Thiophene isosteres: synthesis and biological evaluation of 3-substituted derivatives of 4-phenyl-2-thioxo-benzo [4, 5] thieno [2, 3-d] pyrimidine. European journal of medicinal chemistry, 1991, 26(3): 323-329. |
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Chemical & Physical Properties
| Density | 1.26g/cm3 |
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| Boiling Point | 483.8ºC at 760mmHg |
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| Molecular Formula | C19H18N2O2 |
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| Molecular Weight | 306.35800 |
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| Flash Point | 246.4ºC |
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| Exact Mass | 306.13700 |
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| PSA | 44.12000 |
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| LogP | 3.48210 |
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| Index of Refraction | 1.653 |
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| InChIKey | VAFNJIFAZJWWNI-UHFFFAOYSA-N |
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| SMILES | COc1ccc2c(c1)c(-c1ccccc1)nc(=O)n2CC1CC1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- VA3100333
- CHEMICAL NAME :
- 2(1H)-Quinazolinone, 1-(cyclopropylmethyl)-6-methoxy-4-phenyl-
- CAS REGISTRY NUMBER :
- 33453-23-5
- BEILSTEIN REFERENCE NO. :
- 0761592
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C19-H18-N2-O2
- MOLECULAR WEIGHT :
- 306.39
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3 gm/kg/30D-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Related to Chronic Data - changes in testicular weight
- REFERENCE :
- KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 13,1991,1979
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9100 mg/kg/13W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 13,1991,1979
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Synonyms
| 1-Cyclopropylmethyl-4-phenyl-6-methoxy-2(1H)-chinazolinon |
| 1-Cyclopropylmethyl-4-phenyl-6-methoxy-2(1H)-quinazolinone |
| 1-cyclopropylmethyl-6-methoxy-4-phenyl-1H-quinazolin-2-one |
| Ciproquazonum [INN-Latin] |
| CIPROQUAZONE |
| SL-573 |
| Ciproquazona |
| 1-(Cyclopropyl-methyl)-4-phenyl-6-methoxy-1H-chinazolinon-(2) |
| 2(1H)-Quinazolinone,1-(cyclopropylmethyl)-6-methoxy-4-phenyl |
| 1-(Cyclopropylmethyl)-6-methoxy-4-phenyl-2(1H)-quinazolinone |
| Ciproquazona [INN-Spanish] |
