CAS 189450-19-9|Cortistatin-17 (human) trifluoroacetate salt

Introduction:Basic information about CAS 189450-19-9|Cortistatin-17 (human) trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameCortistatin-17 (human) trifluoroacetate salt
CAS Number189450-19-9Molecular Weight2153.51000
Density/Boiling Point/
Molecular FormulaC96H141N27O24S3Melting Point/
MSDS/Flash Point/

Names

Namecortistatin-17 (human)
SynonymMore Synonyms

BiologicalActivity

DescriptionCortistatin-17 (human) is a somatostatin neuropeptide with potential for studying diseases such as cancer, inflammation, autoimmunity, fibrosis, and pain[1][2].
Related CatalogResearch Areas >>CancerSignaling Pathways >>GPCR/G Protein >>Somatostatin ReceptorResearch Areas >>Inflammation/Immunology
References

[1]. Spier AD, et al. Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions. Brain Res Brain Res Rev. 2000 Sep;33(2-3):228-41.  

[2]. Campos-Salinas J, et al. Therapeutic Effect of a Latent Form of Cortistatin in Experimental Inflammatory and Fibrotic Disorders. Pharmaceutics. 2022 Dec 13;14(12):2785.  

Chemical & Physical Properties

Molecular FormulaC96H141N27O24S3
Molecular Weight2153.51000
Exact Mass2151.98000
PSA955.74000
LogP3.21060
InChIKeyPGMSRFQNSMZWEA-XOJLFHOJSA-N
SMILESCSCCC(NC(=O)C(CCCNC(=N)N)NC(=O)C(N)CC(=O)O)C(=O)N1CCCC1C(=O)NC(CS)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(N)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCCCN)C(=O)NC(C(=O)NC(Cc1ccccc1)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(CS)C(=O)NC(CCCCN)C(=O)O)C(C)O

Synonyms

m.w. 2151.53 c96h139n27o24s3
h-asp-arg-met-pro-cys-arg-asn-phe-phe-trp-lys-thr-phe-ser-ser-cys-lys-oh
asp-arg-met-pro-cys-arg-asn-phe-phe-trp-lys-thr-phe-ser-ser-cys-lys
Cortistatin-17, human
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