Introduction：Basic information about CAS 65-82-7|N-acetyl-L-methionine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-acetyl-L-methionine |
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| CAS Number | 65-82-7 | Molecular Weight | 191.248 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 371.3±52.0 °C at 760 mmHg |
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| Molecular Formula | C7H13NO3S | Melting Point | 104-107ºC |
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| MSDS | Chinese | Flash Point | 178.3±30.7 °C |
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Names
| Name | N-acetyl-L-methionine |
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| Synonym | More Synonyms |
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N-acetyl-L-methionine BiologicalActivity
| Description | N-Acetyl-L-methionine, a human metabolite, is nutritionally and metabolically equivalent to L-methionine. L-methionine is an indispensable amino acid required for normal growth and development[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
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| References | [1]. Ball RO, et al. The in vivo sparing of methionine by cysteine in sulfur amino acid requirements in animal models and adult humans. J Nutr. 2006 Jun;136(6 Suppl):1682S-1693S. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 371.3±52.0 °C at 760 mmHg |
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| Melting Point | 104-107ºC |
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| Molecular Formula | C7H13NO3S |
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| Molecular Weight | 191.248 |
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| Flash Point | 178.3±30.7 °C |
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| Exact Mass | 191.061615 |
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| PSA | 91.70000 |
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| LogP | 0.95 |
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| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
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| Index of Refraction | 1.532 |
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| InChIKey | XUYPXLNMDZIRQH-LURJTMIESA-N |
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| SMILES | CSCCC(NC(C)=O)C(=O)O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- PD0480000
- CHEMICAL NAME :
- Methionine, N-acetyl-
- CAS REGISTRY NUMBER :
- 65-82-7
- BEILSTEIN REFERENCE NO. :
- 1725552
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C7-H13-N-O3-S
- MOLECULAR WEIGHT :
- 191.27
- WISWESSER LINE NOTATION :
- 1VMYVQ2S1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 435 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,262,1970
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | PD0480000 |
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| HS Code | 29309070 |
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Customs
Articles25
More Articles
| Importance of product inhibition in the kinetics of the acylase hydrolysis reaction by differential stopped flow microcalorimetry. Anal. Biochem. 308 , 285-293, (2002) The hydrolysis of N-acetyl-L-methionine, N-acetylglycine, N-acetyl-L-phenylalanine, and N-acetyl-L-alanine at 298.35K by porcine kidney acylase I (EC 3.5.1.14) was monitored by the heat released upon ... | |
| Model sclerotization studies. 4. Generation of N-acetylmethionyl catechol adducts during tyrosinase-catalyzed oxidation of catechols in the presence of N-acetylmethionine. Arch. Insect Biochem. Physiol. 38(1) , 44-52, (1998) Incubation of catechol with mushroom tyrosinase in the presence of N-acetylmethionine resulted in the generation of an adduct. This product was identified to be N-acetylmethionyl catechol, on the basi... | |
| Identification of N-acetylmethionine as the product released during the NH2-terminal processing of a pseudo-class I actin. J. Biol. Chem. 264(19) , 11491-6, (1989) Genes for the various isoactins define two classes of actin. Class I actin genes code for Met-Asp(Glu)-actin, and class II actin genes code for Met-X-Asp(Glu)-actin where X is usually cysteine. Amino ... | |
Synonyms
| EINECS 200-617-7 |
| MFCD00064441 |
| N-Acetyl-L-methionine |
| N-acetyl-methionine |
| Thiomedon |
| L-Methionine, N-acetyl- |
| (2S)-2-acetamido-4-methylsulfanylbutanoic acid |
| Acetylmethionine |
| Methionine, N-acetyl-, L- |
| Methionamine |
| L-N-Acetyl-Methionine |
| L-(N-Acetyl)methionine |
| Ac-Met-OH |
