Introduction：Basic information about CAS 987-02-0|Demecycline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Demecycline |
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| CAS Number | 987-02-0 | Molecular Weight | 430.40800 |
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| Density | 1.69g/cm3 | Boiling Point | 693.5ºC at 760mmHg |
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| Molecular Formula | C21H22N2O8 | Melting Point | / |
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| MSDS | / | Flash Point | 373.2ºC |
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Names
| Name | (4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide |
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| Synonym | More Synonyms |
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Demecycline BiologicalActivity
| Description | Demecycline is the C6-demethylated derivative of Tetracycline (HY-A0107) against bacterial infections including pneumonia and other respiratory tract infections[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. Yang W, Kong L, Wang Q, Deng Z, You D. Metabolic engineering of a methyltransferase for production of drug precursors demecycline and demeclocycline in Streptomyces aureofaciens. Synth Syst Biotechnol. 2020;5(3):121-130. Published 2020 Jun 23. [2]. Results from the Swedish national screening programme 2005. |
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Chemical & Physical Properties
| Density | 1.69g/cm3 |
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| Boiling Point | 693.5ºC at 760mmHg |
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| Molecular Formula | C21H22N2O8 |
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| Molecular Weight | 430.40800 |
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| Flash Point | 373.2ºC |
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| Exact Mass | 430.13800 |
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| PSA | 182.61000 |
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| LogP | 0.76120 |
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| Index of Refraction | 1.757 |
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| InChIKey | RMVMLZHPWMTQGK-SOUFLCLCSA-N |
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| SMILES | CN(C)C1C(=O)C(C(N)=O)=C(O)C2(O)C(=O)C3=C(O)c4c(O)cccc4C(O)C3CC12 |
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Synonyms
| A IX |
| Demecycline |
| Demethyltetracycline |
| Demecyclinum |
| Demeciclina |
| Demecycline (USAN/INN) |
| 6-Demethyltetracyclin |
