CAS 79416-27-6|Methyl aminolevulinate hydrochloride

Introduction:Basic information about CAS 79416-27-6|Methyl aminolevulinate hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameMethyl aminolevulinate hydrochloride
CAS Number79416-27-6Molecular Weight181.617
Density/Boiling Point228ºC at 760 mmHg
Molecular FormulaC6H12ClNO3Melting Point122 °C
MSDSChineseUSAFlash Point99.5ºC
Symbol
GHS07
Signal WordWarning

Names

Namemethyl 5-aminolevulinate hydrochloride
SynonymMore Synonyms

Methyl aminolevulinate hydrochloride BiologicalActivity

DescriptionMethyl aminolevulinate hydrochloride is an agent used as a sensitizer in photodynamic therapy (PDT). Methyl aminolevulinate is a prodrug that can be metabolized to Protoporphyrin IX[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References

[1]. Methyl aminolevulinate, From Wikipedia

Chemical & Physical Properties

Boiling Point228ºC at 760 mmHg
Melting Point122 °C
Molecular FormulaC6H12ClNO3
Molecular Weight181.617
Flash Point99.5ºC
Exact Mass181.050568
PSA69.39000
LogP0.96970
InChIKeyUJYSYPVQHFNBML-UHFFFAOYSA-N
SMILESCOC(=O)CCC(=O)CN.Cl
Storage condition2-8°C

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH315-H319-H335
Precautionary StatementsP261-P305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXi: Irritant;
Risk PhrasesR36/37/38
Safety PhrasesS26-S36
RIDADRNONH for all modes of transport
WGK Germany3
HS Code2922509090

Customs

HS Code2922509090
Summary2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles5

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Multidimensional visualization of healthy and sensitized rabbit knee tissues by means of confocal microscopy.

J. Biomed. Opt. 20 , 051035, (2015)

This study combines several fluorescence detection methods to distinguish structural features of the synovium and cartilage tissues and to visualize the localization of endogenous porphyrins in the se...

Photodynamic therapy for acne vulgaris: a critical review from basics to clinical practice: part I. Acne vulgaris: when and why consider photodynamic therapy? Sakamoto FH, Lopes JD, Anderson RR.

J. Am. Acad. Dermatol. 63 , 193-194, (2010)

Photodynamic therapy: current evidence and applications in dermatology.

Semin. Cutan. Med. Surg. 30 , 199-209, (2011)

Photodynamic therapy (PDT) involves the activation of a photosensitizing drug, which preferentially localizes to diseased skin, by irradiation with light to cause selective cytotoxic damage. Since its...

Synonyms

MFCD00012868
Pentanoic acid, 5-amino-4-oxo-, methyl ester, hydrochloride (1:1)
Metvixia
Methyl 5-amino-4-oxopentanoate hydrochloride (1:1)
Methyl aminolevulinate hydrochloride
methyl 5-amino-4-oxopentanoate,hydrochloride
Methyl 5-Aminolevulinate Hydrochloride
EINECS 279-151-1
5-Aminolevulinic acid methyl ester HCl
Metvix PDT
5-Aminolevulinic acid methyl ester hydrochloride
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