CAS 58479-68-8|Platycodin D

Introduction:Basic information about CAS 58479-68-8|Platycodin D, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NamePlatycodin D
CAS Number58479-68-8Molecular Weight1225.324
Density1.6±0.1 g/cm3Boiling Point/
Molecular FormulaC57H92O28Melting Point/
MSDSChineseUSAFlash Point/

Names

NamePlatycodin D
SynonymMore Synonyms

Platycodin D BiologicalActivity

DescriptionPlatycodin D is a saponin isolated from Platycodi Radix, acts as an activator of AMPKα, with anti-obesity property[1].
Related CatalogSignaling Pathways >>Epigenetics >>AMPKSignaling Pathways >>PI3K/Akt/mTOR >>AMPKResearch Areas >>Metabolic Disease
Target

AMPKα[1]

References

[1]. Kim HL, et al. Platycodin D, a novel activator of AMP-activated protein kinase, attenuates obesity in db/db mice via regulation of adipogenesis and thermogenesis. Phytomedicine. 2019 Jan;52:254-263.

Chemical & Physical Properties

Density1.6±0.1 g/cm3
Molecular FormulaC57H92O28
Molecular Weight1225.324
Exact Mass1224.577515
PSA453.28000
LogP-0.69
Index of Refraction1.659
InChIKeyCYBWUNOAQPMRBA-NDTOZIJESA-N
SMILESCC1OC(OC2C(OC(=O)C34CCC(C)(C)CC3C3=CCC5C6(C)CC(O)C(OC7OC(CO)C(O)C(O)C7O)C(CO)(CO)C6CCC5(C)C3(C)CC4O)OCC(O)C2O)C(O)C(O)C1OC1OCC(O)C(OC2OCC(O)(CO)C2O)C1O
Storage condition2~8°C

Safety Information

Hazard CodesXi
Safety Phrases24/25
RIDADRNONH for all modes of transport
RTECSRK0177962

Synonyms

α-L-Arabinopyranose, O-3-O-[(2S,3R,4R)-tetrahydro-3,4-dihydroxy-4-(hydroxymethyl)-2-furanyl]-β-D-xylopyranosyl-(1->4)-O-6-deoxy-α-L-mannopyranosyl-(1->2)-1-O-[(2β,3β,16α)-3-(β- 
D-glucopyranosyloxy)-2,16,23,24-tetrahydroxy-28-oxoolean-12-en-28-yl]-
PlatycodinD
Platycodin
3-O-[(2S,3R,4R)-3,4-Dihydroxy-4-(hydroxymethyl)tetrahydro-2-furanyl]-β-D-xylopyranosyl-(1->4)-6-deoxy-α-L-mannopyranosyl-(1->2)-1-O-[(2β,3β,16α)-3-(β-D-glucopyranosyloxy)-2,16,23,2 ; 4-tetrahydroxy-28-oxoolean-12-en-28-yl]-α-L-arabinopyranose
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