CAS 459-80-3|GERANIC ACID
| Common Name | GERANIC ACID | ||
|---|---|---|---|
| CAS Number | 459-80-3 | Molecular Weight | 168.23300 |
| Density | 0.97 g/mL at 25 °C(lit.) | Boiling Point | 250 °C(lit.) |
| Molecular Formula | C10H16O2 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | >230 °F |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | geranic acid |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 0.97 g/mL at 25 °C(lit.) |
|---|---|
| Boiling Point | 250 °C(lit.) |
| Molecular Formula | C10H16O2 |
| Molecular Weight | 168.23300 |
| Flash Point | >230 °F |
| Exact Mass | 168.11500 |
| PSA | 37.30000 |
| LogP | 2.76370 |
| Vapour Pressure | 0.000373mmHg at 25°C |
| Index of Refraction | n20/D 1.484(lit.) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,785,1979 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,785,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 34,1196,1940
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,785,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5193 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 1557 (estimated) No. of Female Employees: 276 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H312-H315 |
| Precautionary Statements | P280 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn: Harmful;Xi: Irritant; |
| Risk Phrases | R21 |
| Safety Phrases | S36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | RG5380000 |
| HS Code | 2916190090 |
Customs
| HS Code | 2916190090 |
|---|---|
| Summary | 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0% |
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| Inhibitory effects of geranic acid derivatives on melanin biosynthesis. J. Cosmet. Sci. 63(6) , 351-8, (2012) The effects of geranic acid and its structurally related derivatives (geraniol, citronellic acid, and citronellol) on cell viability and melanin biosynthesis in Melan-a cells were evaluated in this st... |
Synonyms
| MFCD00036493 |
| decaprenoic acid |
| 3,7-dimethyl-6-octadienoicacid |
| 2.6-Dimethyl-heptadien-(1.5)-carbonsaeure-(1) |
| GERANID |
| geranoic acid |
| 3,7-dimethyl-2,6-octadenoic acid |
| 6-Octadienoicacid,3,7-dimethyl-2 |
| 3,7-Dimethyl-octa-2,6-diensaeure |
| 3,7-dimethylocta-2,6-dienoic acid |
| Geranic acid |
| RARECHEM AL BO 0140 |
| (Z,E)-3,7-dimethyl-2,6-octadienoic acid |
| Geraniumsaeure |
| 3,7-DIMETHYL-2,6-OCTADIENOIC ACID |
| EINECS 207-299-9 |
