CAS 286-20-4|Cyclohexene oxide

Introduction：Basic information about CAS 286-20-4|Cyclohexene oxide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles28
7. Synonyms

Common Name	Cyclohexene oxide
CAS Number	286-20-4	Molecular Weight	98.143
Density	1.0±0.1 g/cm3	Boiling Point	130.3±8.0 °C at 760 mmHg
Molecular Formula	C₆H₁₀O	Melting Point	-40 °C
MSDS	ChineseUSA	Flash Point	27.2±0.0 °C
Symbol	GHS02, GHS05, GHS06	Signal Word	Danger

Names

Name	7-oxabicyclo[4.1.0]heptane
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	130.3±8.0 °C at 760 mmHg
Melting Point	-40 °C
Molecular Formula	C₆H₁₀O
Molecular Weight	98.143
Flash Point	27.2±0.0 °C
Exact Mass	98.073166
PSA	12.53000
LogP	1.24
Vapour Pressure	12.0±0.2 mmHg at 25°C
Index of Refraction	1.480
InChIKey	ZWAJLVLEBYIOTI-UHFFFAOYSA-N
SMILES	C1CCC2OC2C1
Water Solubility	INSOLUBLE

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RN7175000

CHEMICAL NAME :: 7-Oxabicyclo(4.1.0)heptane

CAS REGISTRY NUMBER :: 286-20-4

LAST UPDATED :: 199710

DATA ITEMS CITED :: 16

MOLECULAR FORMULA :: C6-H10-O

MOLECULAR WEIGHT :: 98.16

WISWESSER LINE NOTATION :: T36 BOTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1090 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2000 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 549 mg/kg

TOXIC EFFECTS :: Behavioral - tremor

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 630 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 79 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 5 mmol/L

REFERENCE :: CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 51,77,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4047 No. of Facilities: 40 (estimated) No. of Industries: 3 No. of Occupations: 4 No. of Employees: 2874 (estimated) No. of Female Employees: 382 (estimated)

Safety Information

Symbol	GHS02, GHS05, GHS06
Signal Word	Danger
Hazard Statements	H226-H302-H311 + H331-H314
Precautionary Statements	P261-P280-P305 + P351 + P338-P310
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	C:Corrosive;
Risk Phrases	R10;R20/21/22;R34
Safety Phrases	S26-S36/37/39-S45-S16
RIDADR	UN 2924 3/PG 3
WGK Germany	1
RTECS	RN7175000
Packaging Group	II
Hazard Class	8
HS Code	29109000

Customs

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles28

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Eur. J. Med. Chem. 100 , 50-67, (2015)

To verify vesamicol as lead structure in the development of radioligands for imaging of VAChT in the brain by PET, we systematically modified this molecule and investigated four different groups of de...

A Mild Catalytic Oxidation System: FePcOTf/H2O2 Applied for Cyclohexene Dihydroxylation.

Molecules 20 , 8429-39, (2015)

Iron (III) phthalocyanine complexes were employed for the first time as a mild and efficient Lewis acid catalyst in the selective oxidation of cyclohexene to cyclohexane-1,2-diol. It was found that th...

Oviductal microsomal epoxide hydrolase (EPHX1) reduces reactive oxygen species (ROS) level and enhances preimplantation mouse embryo development.

Biol. Reprod. 81(1) , 126-32, (2009)

Somatic cell-embryo coculture enhances embryo development in vitro by producing embryotrophic factor(s) and/or removing harmful substances from the culture environment. Yet, the underlying molecular m...

Synonyms

1,2-Cyclohexene oxide

Tetramethyleneoxirane

Cyclohexene oxide

7-Oxabicyclo[4.1.0]heptane

Cyclohexylene oxide

Cyclohexene 1-oxide

3,4-diepoxycyclohexane

EINECS 206-007-7

cyclohexane-1,2-epoxide

MFCD00005162

3,4-epoxycyclohexane

1,2-Epoxycyclohexane

Cyclohexene epoxide

1,2-Epoxycyclohexane,7-Oxabicyclo[4.1.0]heptane

Cyclohexane,1,2-epoxy

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