Introduction：Basic information about CAS 58-95-7|alpha-Tocopherol acetate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | alpha-Tocopherol acetate |
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| CAS Number | 58-95-7 | Molecular Weight | 472.743 |
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| Density | 0.9±0.1 g/cm3 | Boiling Point | 184 ºC |
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| Molecular Formula | C31H52O3 | Melting Point | 28 ºC |
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| MSDS | ChineseUSA | Flash Point | 235.6±24.7 °C |
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Names
| Name | D-alpha-Tocopheryl acetate |
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| Synonym | More Synonyms |
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alpha-Tocopherol acetate BiologicalActivity
| Description | D-α-Tocopherol acetate (D-Vitamin E acetate) can be hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine[1]. |
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| Related Catalog | Research Areas >>Metabolic Disease |
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| References | [1]. Fukui E, et al. Enhancing effect of medium-chain triglycerides on intestinal absorption of d-alpha-tocopherol acetate from lecithin-dispersed preparations in the rat. J Pharmacobiodyn. 1989 Feb;12(2):80-6. |
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Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
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| Boiling Point | 184 ºC |
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| Melting Point | 28 ºC |
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| Molecular Formula | C31H52O3 |
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| Molecular Weight | 472.743 |
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| Flash Point | 235.6±24.7 °C |
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| Exact Mass | 472.391632 |
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| PSA | 35.53000 |
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| LogP | 12.07 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.488 |
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| InChIKey | ZAKOWWREFLAJOT-CEFNRUSXSA-N |
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| SMILES | CC(=O)Oc1c(C)c(C)c2c(c1C)CCC(C)(CCCC(C)CCCC(C)CCCC(C)C)O2 |
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| Water Solubility | <0.1 g/100 mL at 17 ºC |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- GP8280000
- CHEMICAL NAME :
- 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-
- CAS REGISTRY NUMBER :
- 58-95-7
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C31-H52-O3
- MOLECULAR WEIGHT :
- 472.83
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 182 gm/kg/13W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Blood - pigmented or nucleated red blood cells Blood - changes in other cell count (unspecified)
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 24,1043,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80575 No. of Facilities: 149 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 8005 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80575 No. of Facilities: 834 (estimated) No. of Industries: 5 No. of Occupations: 9 No. of Employees: 8113 (estimated) No. of Female Employees: 5676 (estimated)
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves |
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| Safety Phrases | S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 1 |
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| RTECS | GP8280000 |
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Synonyms
| (2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-yl acetate |
| a-Tocopheryl Acetate |
| Vitamin E acetate |
| [2R*(4R*,8R*)]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol Acetate |
| EINECS 231-710-0 |
| Eprolin |
| Tocopheryl acetate |
| E-Vimin |
| Evion |
| MFCD00072052 |
| 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, acetate, (2R)- |
| Vitamin- E acetate |
| D-α-Tocopheryl acetate |
| a-Tocopherol Acetate |
| TOCOPHEROL ACETATE |
