CAS 7704-67-8|Erythromycin Thicyanate

Introduction：Basic information about CAS 7704-67-8|Erythromycin Thicyanate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameErythromycin Thicyanate
CAS Number7704-67-8Molecular Weight792.010
Density/Boiling Point818.4ºC at 760 mmHg
Molecular FormulaC38H68N2O13SMelting Point/
MSDS/Flash Point448.8ºC

Names

NameErythromycin thiocyanate
SynonymMore Synonyms

Erythromycin Thicyanate BiologicalActivity

DescriptionErythromycin thiocyanate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin thiocyanate acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial
In VitroErythromycin inhibits growth of P. falciparum with IC50 and IC90 values of 58.2 μM and 104.0 μM, respectively[1].
References

[1]. Gribble MJ, et al. Erythromycin. Med Clin North Am. 1982 Jan;66(1):79-89.

[2]. Nakornchai S, et al. Activity of azithromycin or erythromycin in combination with antimalarial drugs against multidrug-resistant Plasmodium falciparum in vitro. Acta Trop. 2006 Dec;100(3):185-91. Epub 2006 Nov 28.

Chemical & Physical Properties

Boiling Point818.4ºC at 760 mmHg
Molecular FormulaC38H68N2O13S
Molecular Weight792.010
Flash Point448.8ºC
Exact Mass791.436951
PSA256.50000
LogP2.18288
InChIKeyWVRRTEYLDPNZHR-YZPBMOCRSA-N
SMILESCCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC2OC(C)CC(N(C)C)C2O)C(C)(O)CC(C)C(=O)C(C)C(O)C1(C)O.N#CS

Safety Information

HS Code2941500000

Customs

HS Code2941500000

Synonyms

ErythroMycin Thiocyanate CGMP
ErythroMicyn thiocyanate
ERYTHROMYCIN THIOCYANATE CP2000
erythromycin thiocynante
ERYTHROMYCIN THIOCYANATE NOT LESS THAN 750 U OF ERYFHROMYCIN PER MG
erythromycin A thiocyanate
ERYTHROMYCIN THIOCYNATE
erythromycin thiocyanante
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