Introduction：Basic information about CAS 497-23-4|2(5H)-Furanone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2(5H)-Furanone |
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| CAS Number | 497-23-4 | Molecular Weight | 84.073 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 203.7±0.0 °C at 760 mmHg |
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| Molecular Formula | C4H4O2 | Melting Point | 4-5 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 101.1±0.0 °C |
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Names
| Name | but-2-en-4-olide |
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| Synonym | More Synonyms |
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2(5H)-Furanone BiologicalActivity
| Description | 2(5H)-Furanone is an endogenous metabolite. |
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| Related Catalog | Research Areas >>Metabolic Disease |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 203.7±0.0 °C at 760 mmHg |
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| Melting Point | 4-5 °C(lit.) |
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| Molecular Formula | C4H4O2 |
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| Molecular Weight | 84.073 |
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| Flash Point | 101.1±0.0 °C |
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| Exact Mass | 84.021126 |
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| PSA | 26.30000 |
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| LogP | -0.84 |
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| Vapour Pressure | 0.3±0.4 mmHg at 25°C |
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| Index of Refraction | 1.481 |
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| InChIKey | VIHAEDVKXSOUAT-UHFFFAOYSA-N |
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| SMILES | O=C1C=CCO1 |
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| Storage condition | 2-8°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- LU3453000
- CHEMICAL NAME :
- 2(5H)-Furanone
- CAS REGISTRY NUMBER :
- 497-23-4
- BEILSTEIN REFERENCE NO. :
- 0383585
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C4-H4-O2
- MOLECULAR WEIGHT :
- 84.08
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 1400 mg/kg
- SEX/DURATION :
- female 2 week(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Maternal Effects - menstrual cycle changes or disorders
- REFERENCE :
- ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 123,571,1990
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 1400 mg/kg
- SEX/DURATION :
- female 2 week(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - other effects Endocrine - changes in luteinizing hormone
- REFERENCE :
- ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 123,571,1990
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Safety Information
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
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| Hazard Codes | Xi:Irritant; |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S26 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | LU3453000 |
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| Packaging Group | I; II; III |
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| HS Code | 29322980 |
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Customs
| HS Code | 2932209090 |
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| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Articles41
More Articles
| Comparative safety of the antifouling compound butenolide and 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) to the marine medaka (Oryzias melastigma). Aquat. Toxicol. 149 , 116-25, (2014) This study evaluated the potential adverse effects of butenolide, a promising antifouling compound, using the marine medaka (Oryzias melastigma), a model fish for marine ecotoxicology. The active ingr... | |
| Proteomic changes in brain tissues of marine medaka (Oryzias melastigma) after chronic exposure to two antifouling compounds: butenolide and 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT). Aquat. Toxicol. 157 , 47-56, (2014) SeaNine 211 with active ingredient of 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) has been used as a "green" antifouling agent worldwide but has raised serious biosafety concerns in coastal en... | |
| Alpha, beta-unsaturated lactones 2-furanone and 2-pyrone induce cellular DNA damage, formation of topoisomerase I- and II-DNA complexes and cancer cell death. Toxicol. Lett. 222(1) , 64-71, (2013) The alpha, beta-unsaturated lactones 2-furanone and 2-pyrone are part of the chemical structure of a variety of naturally occurring compounds (e.g., cardenolides, bufadienolides, acetogenins, coumarin... | |
Synonyms
| 5-Hydrofuran-2-one |
| Furan-2(5H)-one |
| 4-Hydroxycrotonic acid γ-lactone |
| 2H-furan-5-one |
| 2-Butenoic acid-γ-lactone |
| EINECS 207-839-3 |
| T5OV EHJ |
| 2-Butenoic acid γ-lactone |
| 2(5H)-Furanone |
| MFCD00005376 |
| 2[5H]-furanone |
| 4-Hydroxy-2-butenoic acid γ-lactone |
| γ-Crotonolactone |
| 2-Buten-1,4-olide |
| 2-Oxo-2,5-dihydrofuran |
| 2-Butenoic acid, 4-hydroxy-, γ-lactone |
