Introduction：Basic information about CAS 4546-54-7|2-amino-9-(β-D-ribofuranosyl)purine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-amino-9-(β-D-ribofuranosyl)purine |
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| CAS Number | 4546-54-7 | Molecular Weight | 267.24 |
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| Density | 2.1±0.1 g/cm3 | Boiling Point | 711.8±70.0 °C at 760 mmHg |
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| Molecular Formula | C10H13N5O4 | Melting Point | 105-115ºC |
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| MSDS | / | Flash Point | 384.3±35.7 °C |
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Names
| Name | 2-Aminopurine Riboside |
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| Synonym | More Synonyms |
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2-amino-9-(β-D-ribofuranosyl)purine BiologicalActivity
| Description | (2R,3R,4S,5R)-2-(2-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (9-pentofuranosyl-9H-purin-2-amine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 2.1±0.1 g/cm3 |
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| Boiling Point | 711.8±70.0 °C at 760 mmHg |
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| Melting Point | 105-115ºC |
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| Molecular Formula | C10H13N5O4 |
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| Molecular Weight | 267.24 |
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| Flash Point | 384.3±35.7 °C |
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| Exact Mass | 267.096741 |
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| PSA | 139.54000 |
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| LogP | -1.40 |
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| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
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| Index of Refraction | 1.907 |
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| InChIKey | JVOJULURLCZUDE-SZDPNDIZSA-N |
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| SMILES | Nc1ncc2ncn(C3OC(CO)C(O)C3O)c2n1 |
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Safety Information
Customs
| HS Code | 2933599090 |
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| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 9H-purine, 2-amino-9-β-d-ribofuranosyl-, |
| 9-(β-D-Ribofuranosyl)-9H-purin-2-amine |
| 9H-Purin-2-amine, 9-β-D-ribofuranosyl- |
| 2-amino-9-(β-D-ribofuranosyl)purine |
| 9H-Purine, 2-amino-9-β-D-ribofuranosyl- |
| 2-(2-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol |
