CAS 18956-16-6|1-(2,4-DIHYDROXY-6-METHOXYPHENYL)-3-PHENYLPROP-2-EN-1-ONE

Introduction：Basic information about CAS 18956-16-6|1-(2,4-DIHYDROXY-6-METHOXYPHENYL)-3-PHENYLPROP-2-EN-1-ONE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name1-(2,4-DIHYDROXY-6-METHOXYPHENYL)-3-PHENYLPROP-2-EN-1-ONE
CAS Number18956-16-6Molecular Weight270.28000
Density1.282g/cm3Boiling Point484.5ºC at 760 mmHg
Molecular FormulaC16H14O4Melting Point/
MSDS/Flash Point182.7ºC

Names

Namecardamonin
SynonymMore Synonyms

BiologicalActivity

DescriptionCardamonin (Cardamomin), a natural flavone isolated from Alpinia katsumadai Hayata, acts as an aryl hydrocarbon receptor (AhR) activator. Cardamonin alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway[1].
Related CatalogSignaling Pathways >>Immunology/Inflammation >>Aryl Hydrocarbon ReceptorSignaling Pathways >>Immunology/Inflammation >>NOD-like Receptor (NLR)Research Areas >>Inflammation/Immunology
Target

NLRP3

References

[1]. Wang K, et al. Cardamonin, a natural flavone, alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway. Biochem Pharmacol. 2018 Sep;155:494-509.

Chemical & Physical Properties

Density1.282g/cm3
Boiling Point484.5ºC at 760 mmHg
Molecular FormulaC16H14O4
Molecular Weight270.28000
Flash Point182.7ºC
Exact Mass270.08900
PSA66.76000
LogP3.00250
Vapour Pressure5.2E-10mmHg at 25°C
Index of Refraction1.657
Storage condition2-8°C

Synonyms

2',4'-dihydroxy-6'-methoxychalkone
Alpinetinchalkon
4',6'-dihydroxy-2'-methoxychalcone
2',4'-Dihydroxy-6'-methoxychalkon
CAS 898368-40-6|5-((4-Ethoxyphenyl)(4-(4-methoxyphenyl)piperazin-1-yl)methyl)-2-ethylthiazolo[3,2-b]
CAS 886915-26-0|2-Ethyl-5-((4-(4-methoxyphenyl)piperazin-1-yl)(thiophen-2-yl)methyl)thiazolo[3,2-b][
Recommended......
CAS 18813-87-1|4-(4-ETHOXY-PHE CAS 180414-94-2|Fmoc-HomoLeu-O CAS 183198-49-4|Iso Desloratad CAS 18654-81-4|(Z)-4-Octenoic CAS 18206-06-9|2,6-Dimethylpyr CAS 1849-49-6|3-Hydroxy-2,5-di CAS 18714-16-4|2-cyano-4-pheny CAS 18711-25-6|1-METHYL-5-NITR CAS 18260-66-7|2,6-difluoro-5- CAS 187949-02-6|Albaconazole CAS 18813-63-3|6-Isoquinolinol CAS 182250-70-0|3,5-bis(tert-b CAS 184044-09-5|Benzyl piperid CAS 1847-63-8|Nafoxidine HCl CAS 1806-34-4|POPOP CAS 18773-95-0|2-Acetylbenzimi CAS 18060-44-1|8-METHYL-2-(4-M CAS 186191-09-3|4-Methoxy-3-(2 CAS 186588-88-5|3-(BENZYLOXY)- CAS 188399-46-4|(1R, 3S, 4R)-e
Disclaimer

This site is a non-commercial website, not accept any sponsorship and advertising. The content is collated from the Internet, does not represent the position of this site, for personal reference only, please distinguish by yourself! The belongs to the original author.

Copyright © 2025 All Rights Reserved.

TOP