Introduction：Basic information about CAS 791-35-5|clofedanol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | clofedanol |
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| CAS Number | 791-35-5 | Molecular Weight | 289.80000 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C17H20ClNO | Melting Point | 120° |
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| MSDS | / | Flash Point | / |
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Names
| Name | 1-(2-chlorophenyl)-3-(dimethylamino)-1-phenylpropan-1-ol |
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| Synonym | More Synonyms |
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clofedanol BiologicalActivity
| Description | Chlophedianol is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs)[1][2]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Others >>Others |
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| References | [1]. Boyd EM, et al. Chlophedianol Hydrochloride: A New Antitussive Agent. Can Med Assoc J. 1960 Dec 17;83(25):1298-301. [2]. Paul IM. Therapeutic options for acute cough due to upper respiratory infections in children. Lung. 2012 Feb;190(1):41-4. |
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Chemical & Physical Properties
| Melting Point | 120° |
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| Molecular Formula | C17H20ClNO |
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| Molecular Weight | 289.80000 |
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| Exact Mass | 289.12300 |
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| PSA | 23.47000 |
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| LogP | 3.52760 |
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| InChIKey | WRCHFMBCVFFYEQ-UHFFFAOYSA-N |
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| SMILES | CN(C)CCC(O)(c1ccccc1)c1ccccc1Cl |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DC7599500
- CHEMICAL NAME :
- Benzhydrol, 2-chloro-alpha-(2-(dimethylamino)ethyl)-
- CAS REGISTRY NUMBER :
- 791-35-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C17-H20-Cl-N-O
- MOLECULAR WEIGHT :
- 289.83
- WISWESSER LINE NOTATION :
- GR BXQR&2N1&1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 109,476,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 70 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,316,1989
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Synonyms
| 3-Dimethylamino-1-phenyl-1-<1-chlor-phenyl>-propanol-(1) |
| Clofedanolum |
| DL-1-Phenyl-1-(2-chlor-phenyl)-3-dimethylamino-propanol-(1) |
| Clophedianol base |
| 1-(2-Chlor-phenyl)-3-dimethylamino-1-phenyl-propan-1-ol |
| Ulo base |
| Chlofedanol |
| Dencyl |
| Clofedano |
| Tussistop |
| chlophedianol |
| chlophedianol hydrochloride |
| Clofedanol |
| Calmotusin |
