Introduction：Basic information about CAS 790-69-2|Loflucarban, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Loflucarban |
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| CAS Number | 790-69-2 | Molecular Weight | 315.19300 |
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| Density | 1.531g/cm3 | Boiling Point | 395ºC at 760 mmHg |
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| Molecular Formula | C13H9Cl2FN2S | Melting Point | / |
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| MSDS | / | Flash Point | 192.7ºC |
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Names
| Name | 1-(3,5-dichlorophenyl)-3-(4-fluorophenyl)thiourea |
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| Synonym | More Synonyms |
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Loflucarban BiologicalActivity
| Description | Loflucarban (Fluonilid) is a potent antimycotic agent. Loflucarban can be used for the research of the ear infections[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Fungal |
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| In Vitro | One hundred-and-eighty-six fungi were isolated from one hundred-and-eighty cases diagnosed as otomycosis. They comprise 59 species of 26 genera of moulds, and 2 genera of yeasts. Fluonilid shows the MIC ranged from > 100 μg/ml to 1 μg/ml for the majority of tested fungi[1]. |
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| References | [1]. Maher A, et al. Otomycosis: an experimental evaluation of six antimycotic agents. J Laryngol Otol. 1982;96(3):205-213. |
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Chemical & Physical Properties
| Density | 1.531g/cm3 |
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| Boiling Point | 395ºC at 760 mmHg |
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| Molecular Formula | C13H9Cl2FN2S |
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| Molecular Weight | 315.19300 |
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| Flash Point | 192.7ºC |
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| Exact Mass | 313.98500 |
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| PSA | 56.15000 |
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| LogP | 5.08740 |
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| Index of Refraction | 1.729 |
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| InChIKey | ZHNUMLOCJMCLIT-UHFFFAOYSA-N |
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| SMILES | Fc1ccc(NC(=S)Nc2cc(Cl)cc(Cl)c2)cc1 |
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| Storage condition | -20℃ |
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Synonyms
| Loflucarban |
| Loflucarbanum [Latin] |
| Loflucarbanum |
| Fluonilid |
| Fluonilide |
| 3,5-Dichloro-4'-fluorothiocarbanilide |
| Fluoro-4-dichloro-3',5'-thiocarbanilide |
