Introduction：Basic information about CAS 6493-06-7|Lisofylline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Lisofylline |
|---|
| CAS Number | 6493-06-7 | Molecular Weight | 280.323 |
|---|
| Density | 1.3±0.1 g/cm3 | Boiling Point | 511.2±56.0 °C at 760 mmHg |
|---|
| Molecular Formula | C13H20N4O3 | Melting Point | 123-125ºC |
|---|
| MSDS | ChineseUSA | Flash Point | 263.0±31.8 °C |
|---|
Names
| Name | (±)-Lisofylline |
|---|
| Synonym | More Synonyms |
|---|
Lisofylline BiologicalActivity
| Description | (±)-Lisofylline ((±)-Lisophylline) is the racemate of Lisofylline. Lisofylline inhibits the generation of phosphatidic acid and free fatty acids. Lisofylline also blocks the release of pro-inflammatory cytokines in oxidative tissue injury, in response to cancer chemotherapy and in experimental sepsis. Lisofylline can be used for Type 1 diabetes research[1]. |
|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/ImmunologyResearch Areas >>Metabolic Disease |
|---|
| References | [1]. Yang Z, et al. Lisofylline: a potential lead for the treatment of diabetes. Biochem Pharmacol. 2005 Jan 1;69(1):1-5. |
|---|
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|
| Boiling Point | 511.2±56.0 °C at 760 mmHg |
|---|
| Melting Point | 123-125ºC |
|---|
| Molecular Formula | C13H20N4O3 |
|---|
| Molecular Weight | 280.323 |
|---|
| Flash Point | 263.0±31.8 °C |
|---|
| Exact Mass | 280.153534 |
|---|
| PSA | 82.05000 |
|---|
| LogP | 0.34 |
|---|
| Appearance of Characters | solid | white |
|---|
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
|---|
| Index of Refraction | 1.621 |
|---|
| InChIKey | NSMXQKNUPPXBRG-UHFFFAOYSA-N |
|---|
| SMILES | CC(O)CCCCn1c(=O)c2c(ncn2C)n(C)c1=O |
|---|
| Storage condition | Refrigerator |
|---|
| Water Solubility | DMSO: soluble |
|---|
Safety Information
| RIDADR | NONH for all modes of transport |
|---|
| WGK Germany | 3 |
|---|
Articles1
More Articles
| Calcitonin gene-related peptide inhibits human immunodeficiency type 1 transmission by Langerhans cells via an autocrine/paracrine feedback mechanism. Acta Physiol. (Oxf.) 213(2) , 432-41, (2015) Peripheral neurones innervating mucosal epithelia are in direct contact with resident immune cells, including Langerhans cells (LCs). Such neurones secrete the neuropeptide calcitonin gene-related pep... | |
Synonyms
| R-1-(5-Hydroxyhexyl)-3,7-dimethylxanthine |
| (R)-3,7-Dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-1H-purine-2,6-dione |
| 1-[(5R)-5-Hydroxyhexyl]-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione |
| Penthydroxifillyne |
| HYDROXY PENTOXIFYLLINE |
| Lisofylline |
| 1-(5-Hydroxyhexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione |
| 1H-Purine-2,6-dione, 3,7-dihydro-1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl- |
| UNII:R99EE080JS |
| 1H-Purine-2,6-dione, 3,7-dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl- |
| ProTec |
| 1H-Purine-2,6-dione, 3,7-dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl-, (R)- |
| 1-[(R)-5-Hydroxyhexyl]theobromine |
| CT 1501R |
