Introduction：Basic information about CAS 98983-40-5|9-(2-Deoxy-2-fluoro-D-arabinofuranosyl)hypoxanthine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 9-(2-Deoxy-2-fluoro-D-arabinofuranosyl)hypoxanthine |
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| CAS Number | 98983-40-5 | Molecular Weight | 270.22 |
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| Density | 2.01 | Boiling Point | 744.8ºC at 760 mmHg |
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| Molecular Formula | C10H11FN4O4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 6H-Purin-6-one,9-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-1,9-dihydro |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | 2’-Deoxy-2’-fluoroarabino inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 2.01 |
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| Boiling Point | 744.8ºC at 760 mmHg |
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| Molecular Formula | C10H11FN4O4 |
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| Molecular Weight | 270.22 |
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| Exact Mass | 270.07600 |
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| PSA | 113.26000 |
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| Index of Refraction | 1.81 |
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| InChIKey | NRVOTDBYJXFINS-GQTRHBFLSA-N |
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| SMILES | O=c1[nH]cnc2c1ncn2C1OC(CO)C(O)C1F |
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Synonyms
| 9H-Fluorene,9-(2-cyclopropyl-2-propenylidene) |
| 9-(2-cyclopropyl-2-propenylidene)fluorene |
