CAS 221877-54-9|Zotarolimus
Introduction：Basic information about CAS 221877-54-9|Zotarolimus, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Zotarolimus | ||
|---|---|---|---|
| CAS Number | 221877-54-9 | Molecular Weight | 966.210 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 1016.2±75.0 °C at 760 mmHg |
| Molecular Formula | C52H79N5O12 | Melting Point | 100-105°C |
| MSDS | / | Flash Point | 568.4±37.1 °C |
Names
| Name | Zotarolimus |
|---|---|
| Synonym | More Synonyms |
Zotarolimus BiologicalActivity
| Description | Zotarolimus is a tetrazole-containing Rapamycin analog which is used as animmunomodulator, and is useful in the treatment of restenosis, immune, and autoimmune diseases. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Cancer |
| References | [1]. Wagner R et al. Rapamycin analogs with reduced systemic exposure. et al. Bioorg Med Chem Lett. 2005 Dec 1, 15(23), 5340-3. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 1016.2±75.0 °C at 760 mmHg |
| Melting Point | 100-105°C |
| Molecular Formula | C52H79N5O12 |
| Molecular Weight | 966.210 |
| Flash Point | 568.4±37.1 °C |
| Exact Mass | 965.572510 |
| PSA | 218.80000 |
| LogP | 3.55 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.586 |
| InChIKey | CGTADGCBEXYWNE-VNODUHINSA-N |
| SMILES | COC1CC2CCC(C)C(O)(O2)C(=O)C(=O)N2CCCCC2C(=O)OC(C(C)CC2CCC(n3cnnn3)C(OC)C2)CC(=O)C(C)C=C(C)C(O)C(OC)C(=O)C(C)CC(C)C=CC=CC=C1C |
| Storage condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
Safety Information
| HS Code | 29349990 |
|---|
Synonyms
| (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-19,30-dimethoxy-12-{(2R)-1-[(1S,3R,4S)-3-methoxy-4-(1H-tetrazol-1-yl)cyclohexyl]-2-propanyl}-15,17,21,23,29,35-hexamethyl-11, ;36-dioxa-4-azatricyclo[30.3.1.0]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone |
| 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-10,21-dimethoxy-3-[(1R)-2-[(1S,3R,4S)-3-methoxy-4-(1H-tetrazol-1-yl)cyclohexyl]-1-methylethyl]-6,8,12,14,20,26-hexamethyl-, (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)- |
| (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-10,21-dimethoxy-3-{(2R)-1-[(1S,3R,4S)-3-methoxy-4-(1H-tetrazol-1-yl)cyclohexyl]propan-2-yl}-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone |
| Zotarolimus |
| ABT-578 |
