CAS 189691-06-3|Bremelanotide PT 141

Introduction：Basic information about CAS 189691-06-3|Bremelanotide PT 141, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Bremelanotide PT 141 BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Bremelanotide PT 141
CAS Number	189691-06-3	Molecular Weight	1025.163
Density	1.4±0.1 g/cm3	Boiling Point	/
Molecular Formula	C₅₀H₆₈N₁₄O₁₀	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	Bremelanotide
Synonym	More Synonyms

Bremelanotide PT 141 BiologicalActivity

Description	Bremelanotide (PT-141) is an analogue of α-melanocyte-stimulating hormone (α-MSH). Bremelanotide activates the mPOA and other hypothalamic and limbic regions of the brain involved in sexual behavior. Bremelanotide can be used for researching hypoactive sexual desire disorders[1].
Related Catalog	Research Areas >>EndocrinologySignaling Pathways >>GPCR/G Protein >>Melanocortin Receptor
References	[1]. Pfaus J, et al. Bremelanotide: an overview of preclinical CNS effects on female sexual function. J Sex Med. 2007 Nov;4 Suppl 4:269-79. [2]. Molinoff PB, et al. PT-141: a melanocortin agonist for the treatment of sexual dysfunction. Ann N Y Acad Sci. 2003 Jun;994:96-102.

Description

Bremelanotide (PT-141) is an analogue of α-melanocyte-stimulating hormone (α-MSH). Bremelanotide activates the mPOA and other hypothalamic and limbic regions of the brain involved in sexual behavior. Bremelanotide can be used for researching hypoactive sexual desire disorders[1].

Related Catalog

Research Areas >>EndocrinologySignaling Pathways >>GPCR/G Protein >>Melanocortin Receptor

References

[1]. Pfaus J, et al. Bremelanotide: an overview of preclinical CNS effects on female sexual function. J Sex Med. 2007 Nov;4 Suppl 4:269-79.

[2]. Molinoff PB, et al. PT-141: a melanocortin agonist for the treatment of sexual dysfunction. Ann N Y Acad Sci. 2003 Jun;994:96-102.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Molecular Formula	C₅₀H₆₈N₁₄O₁₀
Molecular Weight	1025.163
Exact Mass	1024.524292
PSA	376.47000
LogP	-1.21
Index of Refraction	1.679
InChIKey	FFHBJDQSGDNCIV-MFVUMRCOSA-N
SMILES	CCCCC(NC(C)=O)C(=O)NC1CC(=O)NCCCCC(C(=O)O)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCN=C(N)N)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2cnc[nH]2)NC1=O

Synonyms

PT141 Acetate

BreMelanotide Acetate

PT-141

Bremelanotide PT 141

1,4,7,10,13,18-Hexaazacyclotricosane-23-carboxylic acid, 15-[[(2S)-2-(acetylamino)-1-oxohexyl]amino]-6-[3-[(aminoiminomethyl)amino]propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-9-(phenylmethyl)-, (3S,6S,9R,12S,15S,23S)-

(3S,6S,9R,12S,15S,23S)-15-[(N-Acetyl-L-norleucyl)amino]-9-benzyl-6-(3-carbamimidamidopropyl)-12-(1H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxylic acid

Brmelanotice

bremelanotide

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